Dobrowolny G - Search Results

1

Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1^G93A mice.

Scaricamazza S, Salvatori I, Amadio S, Nesci V, Torcinaro A, Giacovazzo G, Primiano A, Gloriani M, Candelise N, Pieroni L, Loeffler JP, Renè F, Quessada C, Tefera TW, Wang H, Steyn FJ, Ngo ST, Dobrowolny G, Lepore E, Urbani A, Musarò A, Volonté C, Ferraro E, Coccurello R, Valle C, Ferri A. Scaricamazza S, et al. Among authors: dobrowolny g. Br J Pharmacol. 2022 Apr;179(8):1732-1752. doi: 10.1111/bph.15738. Epub 2022 Jan 13. Br J Pharmacol. 2022. PMID: 34783031 Free PMC article.

2

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model.

Dobrowolny G, Giacinti C, Pelosi L, Nicoletti C, Winn N, Barberi L, Molinaro M, Rosenthal N, Musarò A. Dobrowolny G, et al. J Cell Biol. 2005 Jan 17;168(2):193-9. doi: 10.1083/jcb.200407021. J Cell Biol. 2005. PMID: 15657392 Free PMC article.

3

The neuroprotective effects of a locally acting IGF-1 isoform.

Musarò A, Dobrowolny G, Rosenthal N. Musarò A, et al. Among authors: dobrowolny g. Exp Gerontol. 2007 Jan-Feb;42(1-2):76-80. doi: 10.1016/j.exger.2006.05.004. Epub 2006 Jun 19. Exp Gerontol. 2007. PMID: 16782294 Review.

4

Local expression of mIgf-1 modulates ubiquitin, caspase and CDK5 expression in skeletal muscle of an ALS mouse model.

Dobrowolny G, Aucello M, Molinaro M, Musarò A. Dobrowolny G, et al. Neurol Res. 2008 Mar;30(2):131-6. doi: 10.1179/174313208X281235. Neurol Res. 2008. PMID: 18397603

5

Skeletal muscle is a primary target of SOD1G93A-mediated toxicity.

Dobrowolny G, Aucello M, Rizzuto E, Beccafico S, Mammucari C, Boncompagni S, Belia S, Wannenes F, Nicoletti C, Del Prete Z, Rosenthal N, Molinaro M, Protasi F, Fanò G, Sandri M, Musarò A. Dobrowolny G, et al. Cell Metab. 2008 Nov;8(5):425-36. doi: 10.1016/j.cmet.2008.09.002. Cell Metab. 2008. PMID: 19046573 Free article.

6

Localized accumulation of oxidative stress causes muscle atrophy through activation of an autophagic pathway.

Aucello M, Dobrowolny G, Musarò A. Aucello M, et al. Among authors: dobrowolny g. Autophagy. 2009 May;5(4):527-9. doi: 10.4161/auto.5.4.7962. Epub 2009 May 28. Autophagy. 2009. PMID: 19221466

7

Muscle involvement and IGF-1 signaling in genetic disorders: new therapeutic approaches.

Barberi L, Dobrowolny G, Pelosi L, Giacinti C, Musarò A. Barberi L, et al. Among authors: dobrowolny g. Endocr Dev. 2009;14:29-37. doi: 10.1159/000207474. Epub 2009 Feb 27. Endocr Dev. 2009. PMID: 19293573 Review.

8

Muscle atrophy induced by SOD1G93A expression does not involve the activation of caspase in the absence of denervation.

Dobrowolny G, Aucello M, Musarò A. Dobrowolny G, et al. Skelet Muscle. 2011 Jan 24;1(1):3. doi: 10.1186/2044-5040-1-3. Skelet Muscle. 2011. PMID: 21798081 Free PMC article.

9

IPLEX administration improves motor neuron survival and ameliorates motor functions in a severe mouse model of spinal muscular atrophy.

Murdocca M, Malgieri A, Luchetti A, Saieva L, Dobrowolny G, de Leonibus E, Filareto A, Quitadamo MC, Novelli G, Musarò A, Sangiuolo F. Murdocca M, et al. Among authors: dobrowolny g. Mol Med. 2012 Sep 25;18(1):1076-85. doi: 10.2119/molmed.2012.00056. Mol Med. 2012. PMID: 22669476 Free PMC article.

10

Postmitotic Expression of SOD1(G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation.

Martini M, Dobrowolny G, Aucello M, Musarò A. Martini M, et al. Among authors: dobrowolny g. Mediators Inflamm. 2015;2015:537853. doi: 10.1155/2015/537853. Epub 2015 Sep 28. Mediators Inflamm. 2015. PMID: 26491230 Free PMC article.

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