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Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK. El-Saafin F, et al. Among authors: dixon m. Cell Death Differ. 2022 May;29(5):1013-1027. doi: 10.1038/s41418-022-00982-5. Epub 2022 Mar 31. Cell Death Differ. 2022. PMID: 35361962 Free PMC article.
Chromatin immunoprecipitation of mouse embryos.
Voss AK, Dixon MP, McLennan T, Kueh AJ, Thomas T. Voss AK, et al. Methods Mol Biol. 2012;809:335-52. doi: 10.1007/978-1-61779-376-9_23. Methods Mol Biol. 2012. PMID: 22113287
Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription.
El-Saafin F, Curry C, Ye T, Garnier JM, Kolb-Cheynel I, Stierle M, Downer NL, Dixon MP, Negroni L, Berger I, Thomas T, Voss AK, Dobyns W, Devys D, Tora L. El-Saafin F, et al. Among authors: dixon mp. Hum Mol Genet. 2018 Jun 15;27(12):2171-2186. doi: 10.1093/hmg/ddy126. Hum Mol Genet. 2018. PMID: 29648665 Free PMC article.
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.
McRae HM, Garnham AL, Hu Y, Witkowski MT, Corbett MA, Dixon MP, May RE, Sheikh BN, Chiang W, Kueh AJ, Nguyen TA, Man K, Gloury R, Aubrey BJ, Policheni A, Di Rago L, Alexander WS, Gray DHD, Strasser A, Hawkins ED, Wilcox S, Gécz J, Kallies A, McCormack MP, Smyth GK, Voss AK, Thomas T. McRae HM, et al. Among authors: dixon mp. Blood. 2019 Apr 18;133(16):1729-1741. doi: 10.1182/blood-2018-07-860726. Epub 2019 Feb 12. Blood. 2019. PMID: 30755422 Free PMC article.
1,765 results