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Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA.
Ngo J, Choi DW, Stanley IA, Stiles L, Molina AJA, Chen PH, Lako A, Sung ICH, Goswami R, Kim MY, Miller N, Baghdasarian S, Kim-Vasquez D, Jones AE, Roach B, Gutierrez V, Erion K, Divakaruni AS, Liesa M, Danial NN, Shirihai OS. Ngo J, et al. Among authors: divakaruni as. EMBO J. 2023 Jun 1;42(11):e111901. doi: 10.15252/embj.2022111901. Epub 2023 Mar 14. EMBO J. 2023. PMID: 36917141 Free PMC article.
Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis.
Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. Divakaruni AS, et al. Cell Metab. 2018 Sep 4;28(3):490-503.e7. doi: 10.1016/j.cmet.2018.06.001. Epub 2018 Jun 28. Cell Metab. 2018. PMID: 30043752 Free PMC article.
ACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP.
Cao DY, Spivia WR, Veiras LC, Khan Z, Peng Z, Jones AE, Bernstein EA, Saito S, Okwan-Duodu D, Parker SJ, Giani JF, Divakaruni AS, Van Eyk JE, Bernstein KE. Cao DY, et al. Among authors: divakaruni as. J Biol Chem. 2020 Jan 31;295(5):1369-1384. doi: 10.1074/jbc.RA119.011244. Epub 2019 Dec 23. J Biol Chem. 2020. PMID: 31871049 Free PMC article.
A novel approach to measure mitochondrial respiration in frozen biological samples.
Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. Acin-Perez R, et al. Among authors: divakaruni as. EMBO J. 2020 Jul 1;39(13):e104073. doi: 10.15252/embj.2019104073. Epub 2020 May 20. EMBO J. 2020. PMID: 32432379 Free PMC article.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner.
Chella Krishnan K, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. Chella Krishnan K, et al. Among authors: divakaruni as. Cell Mol Gastroenterol Hepatol. 2021;11(2):389-406. doi: 10.1016/j.jcmgh.2020.09.004. Epub 2020 Sep 14. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32942044 Free PMC article.
Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling.
Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, Oliveira MF, Shirihai OS. Veliova M, et al. Among authors: divakaruni as. EMBO Rep. 2020 Dec 3;21(12):e49634. doi: 10.15252/embr.201949634. Epub 2020 Dec 4. EMBO Rep. 2020. PMID: 33275313 Free PMC article.
Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells.
Tucci J, Chen T, Margulis K, Orgel E, Paszkiewicz RL, Cohen MD, Oberley MJ, Wahhab R, Jones AE, Divakaruni AS, Hsu CC, Noll SE, Sheng X, Zare RN, Mittelman SD. Tucci J, et al. Among authors: divakaruni as. Front Oncol. 2021 Apr 22;11:665763. doi: 10.3389/fonc.2021.665763. eCollection 2021. Front Oncol. 2021. PMID: 33968771 Free PMC article.
70 results