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Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison.
Himmel HM; Irwin/FOB Consortium Members; Delaunois A, Deurinck M, Dinklo T, Eriksson Faelker TM, Habermann C, Heers C, Hempel K, Lorenz H, Rosch A, Schauerte H, Teuns G, Traebert M, van Amsterdam C, van der Linde H. Himmel HM, et al. Among authors: dinklo t. J Pharmacol Toxicol Methods. 2019 Sep-Oct;99:106571. doi: 10.1016/j.vascn.2019.03.002. Epub 2019 Mar 27. J Pharmacol Toxicol Methods. 2019. PMID: 30928509
Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4-pyridinyl)-5-thiazolemethanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor.
Dinklo T, Shaban H, Thuring JW, Lavreysen H, Stevens KE, Zheng L, Mackie C, Grantham C, Vandenberk I, Meulders G, Peeters L, Verachtert H, De Prins E, Lesage AS. Dinklo T, et al. J Pharmacol Exp Ther. 2011 Feb;336(2):560-74. doi: 10.1124/jpet.110.173245. Epub 2010 Nov 17. J Pharmacol Exp Ther. 2011. PMID: 21084390