Dinarello CA - Search Results

1

Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions.

Dinarello A, Mills TS, Tengesdal IW, Powers NE, Azam T, Dinarello CA. Dinarello A, et al. Among authors: dinarello ca. Cells. 2023 Jan 12;12(2):294. doi: 10.3390/cells12020294. Cells. 2023. PMID: 36672229 Free PMC article.

2

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.

Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Li S, et al. Among authors: dinarello ca. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2497-502. doi: 10.1073/pnas.1424626112. Epub 2015 Feb 5. Proc Natl Acad Sci U S A. 2015. PMID: 25654981 Free PMC article.

3

Pharmacologic inhibition of NLRP3 reduces the levels of α-synuclein and protects dopaminergic neurons in a model of Parkinson's disease.

Amo-Aparicio J, Daly J, Højen JF, Dinarello CA. Amo-Aparicio J, et al. Among authors: dinarello ca. J Neuroinflammation. 2023 Jun 22;20(1):147. doi: 10.1186/s12974-023-02830-w. J Neuroinflammation. 2023. PMID: 37349821 Free PMC article.

4

NLRP3 and cancer: Pathogenesis and therapeutic opportunities.

Tengesdal IW, Dinarello CA, Marchetti C. Tengesdal IW, et al. Among authors: dinarello ca. Pharmacol Ther. 2023 Nov;251:108545. doi: 10.1016/j.pharmthera.2023.108545. Epub 2023 Oct 21. Pharmacol Ther. 2023. PMID: 37866732 Review.

5

Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation.

Jaeger M, Dietschmann A, Austermeier S, Dinçer S, Porschitz P, Vornholz L, Maas RJA, Sprenkeler EGG, Ruland J, Wirtz S, Azam T, Joosten LAB, Hube B, Netea MG, Dinarello CA, Gresnigt MS. Jaeger M, et al. Among authors: dinarello ca. Virulence. 2024 Dec;15(1):2333367. doi: 10.1080/21505594.2024.2333367. Epub 2024 Apr 10. Virulence. 2024. PMID: 38515333 Free PMC article.

6

Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance.

Carta S, Penco F, Lavieri R, Martini A, Dinarello CA, Gattorno M, Rubartelli A. Carta S, et al. Among authors: dinarello ca. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2835-40. doi: 10.1073/pnas.1424741112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25730877 Free PMC article. Clinical Trial.

7

NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma.

Zhai Z, Liu W, Kaur M, Luo Y, Domenico J, Samson JM, Shellman YG, Norris DA, Dinarello CA, Spritz RA, Fujita M. Zhai Z, et al. Among authors: dinarello ca. Oncogene. 2017 Jul 6;36(27):3820-3830. doi: 10.1038/onc.2017.26. Epub 2017 Mar 6. Oncogene. 2017. PMID: 28263976 Free PMC article.

8

The IL-1 family of cytokines and receptors in rheumatic diseases.

Dinarello CA. Dinarello CA. Nat Rev Rheumatol. 2019 Oct;15(10):612-632. doi: 10.1038/s41584-019-0277-8. Epub 2019 Sep 12. Nat Rev Rheumatol. 2019. PMID: 31515542 Review.

9

Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions.

The E, Zhai Y, Yao Q, Ao L, Li S, Fullerton DA, Dinarello CA, Meng X. The E, et al. Among authors: dinarello ca. Int J Biol Sci. 2023 Jul 31;19(12):3908-3919. doi: 10.7150/ijbs.85745. eCollection 2023. Int J Biol Sci. 2023. PMID: 37564205 Free PMC article.

10

Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions.

Lee E, Redzic JS, Nemkov T, Saviola AJ, Dzieciatkowska M, Hansen KC, D'Alessandro A, Dinarello C, Eisenmesser EZ. Lee E, et al. Molecules. 2022 Jul 14;27(14):4494. doi: 10.3390/molecules27144494. Molecules. 2022. PMID: 35889366 Free PMC article.

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