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Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.
Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Myers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, Jordan CT, Di Paola J, Hagman JR, Holers VM, Kuhn KA, Pietras EM. Hernandez G, et al. Among authors: dinarello ca. Haematologica. 2020 Mar;105(3):585-597. doi: 10.3324/haematol.2018.197210. Epub 2019 May 17. Haematologica. 2020. PMID: 31101752 Free PMC article.
Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo.
Hayashi M, Jin Y, Yorgov D, Santorico SA, Hagman J, Ferrara TM, Jones KL, Cavalli G, Dinarello CA, Spritz RA. Hayashi M, et al. Among authors: dinarello ca. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1357-62. doi: 10.1073/pnas.1525001113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787886 Free PMC article.
Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, Pietras EM, DeGregori J, Tan AC, Joosten LAB, Fujita M, Dinarello CA, Marchetti C. Tengesdal IW, et al. Among authors: dinarello ca. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2000915118. doi: 10.1073/pnas.2000915118. Proc Natl Acad Sci U S A. 2021. PMID: 33649199 Free PMC article.
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.
Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, Dagna L, Boletta A, D'Alessandro A, Joosten LAB, Netea MG, Dinarello CA. Cavalli G, et al. Among authors: dinarello ca. Cell Rep. 2021 Apr 6;35(1):108955. doi: 10.1016/j.celrep.2021.108955. Cell Rep. 2021. PMID: 33826894 Free article.
Proinflammatory cytokines in heart disease.
Dinarello CA, Pomerantz BJ. Dinarello CA, et al. Blood Purif. 2001;19(3):314-21. doi: 10.1159/000046960. Blood Purif. 2001. PMID: 11244192 Review.
1,090 results