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Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.
Zhang J, Sharma D, Dinabandhu A, Sanchez J, Applewhite B, Jee K, Deshpande M, Flores-Bellver M, Hu MW, Guo C, Salman S, Hwang Y, Anders NM, Rudek MA, Qian J, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: dinabandhu a. J Clin Invest. 2023 Jul 3;133(13):e163290. doi: 10.1172/JCI163290. J Clin Invest. 2023. PMID: 37227777 Free PMC article.
ANGPTL4 influences the therapeutic response of patients with neovascular age-related macular degeneration by promoting choroidal neovascularization.
Qin Y, Dinabandhu A, Cao X, Sanchez JC, Jee K, Rodrigues M, Guo C, Zhang J, Vancel J, Menon D, Khan NS, Ma T, Tzeng SY, Daoud Y, Green JJ, Semenza GL, Montaner S, Sodhi A. Qin Y, et al. Among authors: dinabandhu a. JCI Insight. 2022 Jul 8;7(13):e157896. doi: 10.1172/jci.insight.157896. JCI Insight. 2022. PMID: 35653189 Free PMC article.
Aqueous proteins help predict the response of patients with neovascular age-related macular degeneration to anti-VEGF therapy.
Cao X, Sanchez JC, Dinabandhu A, Guo C, Patel TP, Yang Z, Hu MW, Chen L, Wang Y, Malik D, Jee K, Daoud YJ, Handa JT, Zhang H, Qian J, Montaner S, Sodhi A. Cao X, et al. Among authors: dinabandhu a. J Clin Invest. 2022 Jan 18;132(2):e144469. doi: 10.1172/JCI144469. J Clin Invest. 2022. PMID: 34874918 Free PMC article. Clinical Trial.
HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease.
Zhang J, Qin Y, Martinez M, Flores-Bellver M, Rodrigues M, Dinabandhu A, Cao X, Deshpande M, Qin Y, Aparicio-Domingo S, Rui Y, Tzeng SY, Salman S, Yuan J, Scott AW, Green JJ, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: dinabandhu a. J Clin Invest. 2021 Jun 15;131(12):e139202. doi: 10.1172/JCI139202. J Clin Invest. 2021. PMID: 34128478 Free PMC article.