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TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells.
Nat Commun. 2020 Jan 23;11(1):454. doi: 10.1038/s41467-019-14262-3.
Nat Commun. 2020.
PMID: 31974393
Free PMC article.
Dealing with saturated and unsaturated fatty acid metabolism for anticancer therapy.
Dierge E, Feron O.
Dierge E, et al.
Curr Opin Clin Nutr Metab Care. 2019 Nov;22(6):427-433. doi: 10.1097/MCO.0000000000000601.
Curr Opin Clin Nutr Metab Care. 2019.
PMID: 31589175
Review.
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Cancer diets for cancer patients: Lessons from mouse studies and new insights from the study of fatty acid metabolism in tumors.
Dierge E, Larondelle Y, Feron O.
Dierge E, et al.
Biochimie. 2020 Nov;178:56-68. doi: 10.1016/j.biochi.2020.08.020. Epub 2020 Sep 3.
Biochimie. 2020.
PMID: 32890677
Review.
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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects.
Dierge E, Debock E, Guilbaud C, Corbet C, Mignolet E, Mignard L, Bastien E, Dessy C, Larondelle Y, Feron O.
Dierge E, et al.
Cell Metab. 2021 Aug 3;33(8):1701-1715.e5. doi: 10.1016/j.cmet.2021.05.016. Epub 2021 Jun 11.
Cell Metab. 2021.
PMID: 34118189
Free article.
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Punicic Acid Triggers Ferroptotic Cell Death in Carcinoma Cells.
Vermonden P, Vancoppenolle M, Dierge E, Mignolet E, Cuvelier G, Knoops B, Page M, Debier C, Feron O, Larondelle Y.
Vermonden P, et al. Among authors: dierge e.
Nutrients. 2021 Aug 10;13(8):2751. doi: 10.3390/nu13082751.
Nutrients. 2021.
PMID: 34444911
Free PMC article.
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Targeting cancer cells in acidosis with conjugates between the carnitine palmitoyltransferase 1 inhibitor etomoxir and pH (low) insertion peptides.
Deskeuvre M, Lan J, Dierge E, Messens J, Riant O, Corbet C, Feron O, Frédérick R.
Deskeuvre M, et al. Among authors: dierge e.
Int J Pharm. 2022 Aug 25;624:122041. doi: 10.1016/j.ijpharm.2022.122041. Epub 2022 Jul 20.
Int J Pharm. 2022.
PMID: 35868479
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