Diamond MI - Search Results

1

Huntington disease and the huntingtin protein.

Zheng Z, Diamond MI. Zheng Z, et al. Among authors: diamond mi. Prog Mol Biol Transl Sci. 2012;107:189-214. doi: 10.1016/B978-0-12-385883-2.00010-2. Prog Mol Biol Transl Sci. 2012. PMID: 22482451 Review.

2

Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice.

Li M, Huang Y, Ma AA, Lin E, Diamond MI. Li M, et al. Among authors: diamond mi. Neurobiol Dis. 2009 Dec;36(3):413-20. doi: 10.1016/j.nbd.2009.06.011. Epub 2009 Jul 8. Neurobiol Dis. 2009. PMID: 19591939

3

Cellular mechanisms of protein aggregate propagation.

Holmes BB, Diamond MI. Holmes BB, et al. Among authors: diamond mi. Curr Opin Neurol. 2012 Dec;25(6):721-6. doi: 10.1097/WCO.0b013e32835a3ee0. Curr Opin Neurol. 2012. PMID: 23108252 Free PMC article. Review.

4

An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1.

Zheng Z, Li A, Holmes BB, Marasa JC, Diamond MI. Zheng Z, et al. Among authors: diamond mi. J Biol Chem. 2013 Mar 1;288(9):6063-71. doi: 10.1074/jbc.M112.413575. Epub 2013 Jan 14. J Biol Chem. 2013. PMID: 23319588 Free PMC article.

5

Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease.

Li M, Yasumura D, Ma AA, Matthes MT, Yang H, Nielson G, Huang Y, Szoka FC, Lavail MM, Diamond MI. Li M, et al. Among authors: diamond mi. PLoS One. 2013;8(2):e56026. doi: 10.1371/journal.pone.0056026. Epub 2013 Feb 11. PLoS One. 2013. PMID: 23409115 Free PMC article.

6

N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice.

Gu X, Cantle JP, Greiner ER, Lee CY, Barth AM, Gao F, Park CS, Zhang Z, Sandoval-Miller S, Zhang RL, Diamond M, Mody I, Coppola G, Yang XW. Gu X, et al. Neuron. 2015 Feb 18;85(4):726-41. doi: 10.1016/j.neuron.2015.01.008. Epub 2015 Feb 5. Neuron. 2015. PMID: 25661181 Free PMC article.

7

Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.

DeVos SL, Miller RL, Schoch KM, Holmes BB, Kebodeaux CS, Wegener AJ, Chen G, Shen T, Tran H, Nichols B, Zanardi TA, Kordasiewicz HB, Swayze EE, Bennett CF, Diamond MI, Miller TM. DeVos SL, et al. Among authors: diamond mi. Sci Transl Med. 2017 Jan 25;9(374):eaag0481. doi: 10.1126/scitranslmed.aag0481. Sci Transl Med. 2017. PMID: 28123067 Free PMC article.

8

Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers.

Posey AE, Ruff KM, Harmon TS, Crick SL, Li A, Diamond MI, Pappu RV. Posey AE, et al. Among authors: diamond mi. J Biol Chem. 2018 Mar 9;293(10):3734-3746. doi: 10.1074/jbc.RA117.000357. Epub 2018 Jan 22. J Biol Chem. 2018. PMID: 29358329 Free PMC article.

9

Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor.

Diamond MI, Robinson MR, Yamamoto KR. Diamond MI, et al. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):657-61. doi: 10.1073/pnas.97.2.657. Proc Natl Acad Sci U S A. 2000. PMID: 10639135 Free PMC article.

10

Biologically active molecules that reduce polyglutamine aggregation and toxicity.

Desai UA, Pallos J, Ma AA, Stockwell BR, Thompson LM, Marsh JL, Diamond MI. Desai UA, et al. Among authors: diamond mi. Hum Mol Genet. 2006 Jul 1;15(13):2114-24. doi: 10.1093/hmg/ddl135. Epub 2006 May 23. Hum Mol Genet. 2006. PMID: 16720620

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