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MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease.
Demers M, Sturtevant S, Guertin KR, Gupta D, Desai K, Vieira BF, Li W, Hicks A, Ismail A, Gonçalves BP, Di Caprio G, Schonbrun E, Hansen S, Musayev FN, Safo MK, Wood DK, Higgins JM, Light DR. Demers M, et al. Among authors: di caprio g. Blood Adv. 2021 Mar 9;5(5):1388-1402. doi: 10.1182/bloodadvances.2020003670. Blood Adv. 2021. PMID: 33661300 Free PMC article.
Dye exclusion microfluidic microscopy.
Schonbrun E, Di Caprio G, Schaak D. Schonbrun E, et al. Among authors: di caprio g. Opt Express. 2013 Apr 8;21(7):8793-8. doi: 10.1364/OE.21.008793. Opt Express. 2013. PMID: 23571968 Free article.
Hyperspectral fluorescence microfluidic (HFM) microscopy.
Di Caprio G, Schaak D, Schonbrun E. Di Caprio G, et al. Biomed Opt Express. 2013 Jul 31;4(8):1486-93. doi: 10.1364/BOE.4.001486. eCollection 2013. Biomed Opt Express. 2013. PMID: 24010010 Free PMC article.
Polarization encoded color camera.
Schonbrun E, Möller G, Di Caprio G. Schonbrun E, et al. Among authors: di caprio g. Opt Lett. 2014 Mar 15;39(6):1433-6. doi: 10.1364/OL.39.001433. Opt Lett. 2014. PMID: 24690806
Single-cell measurement of red blood cell oxygen affinity.
Di Caprio G, Stokes C, Higgins JM, Schonbrun E. Di Caprio G, et al. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9984-9. doi: 10.1073/pnas.1509252112. Epub 2015 Jul 27. Proc Natl Acad Sci U S A. 2015. PMID: 26216973 Free PMC article.
Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling.
De Souza DC, Hebert N, Esrick EB, Ciuculescu MF, Archer NM, Armant M, Audureau É, Brendel C, Di Caprio G, Galactéros F, Liu D, McCabe A, Morris E, Schonbrun E, Williams D, Wood DK, Williams DA, Bartolucci P, Higgins JM. De Souza DC, et al. Among authors: di caprio g. Nat Commun. 2023 Sep 20;14(1):5850. doi: 10.1038/s41467-023-40923-5. Nat Commun. 2023. PMID: 37730674 Free PMC article.
74 results