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Map3k1 Loss Cooperates with BrafV600E to Drive Melanomagenesis.
Trucco LD, Mundra PA, García-Martínez P, Hogan K, Baenke F, Dhomen N, Pavet V, Marais R. Trucco LD, et al. Among authors: dhomen n. J Invest Dermatol. 2021 Jan;141(1):221-225.e6. doi: 10.1016/j.jid.2020.05.085. Epub 2020 May 22. J Invest Dermatol. 2021. PMID: 32450073 Free article. Review. No abstract available.
New insight into BRAF mutations in cancer.
Dhomen N, Marais R. Dhomen N, et al. Curr Opin Genet Dev. 2007 Feb;17(1):31-9. doi: 10.1016/j.gde.2006.12.005. Curr Opin Genet Dev. 2007. PMID: 17208430 Review.
Oncogenic Braf induces melanocyte senescence and melanoma in mice.
Dhomen N, Reis-Filho JS, da Rocha Dias S, Hayward R, Savage K, Delmas V, Larue L, Pritchard C, Marais R. Dhomen N, et al. Cancer Cell. 2009 Apr 7;15(4):294-303. doi: 10.1016/j.ccr.2009.02.022. Cancer Cell. 2009. PMID: 19345328 Free article.
BRAF signaling and targeted therapies in melanoma.
Dhomen N, Marais R. Dhomen N, et al. Hematol Oncol Clin North Am. 2009 Jun;23(3):529-45, ix. doi: 10.1016/j.hoc.2009.04.001. Hematol Oncol Clin North Am. 2009. PMID: 19464601 Review.
A mouse model of melanoma driven by oncogenic KRAS.
Milagre C, Dhomen N, Geyer FC, Hayward R, Lambros M, Reis-Filho JS, Marais R. Milagre C, et al. Among authors: dhomen n. Cancer Res. 2010 Jul 1;70(13):5549-57. doi: 10.1158/0008-5472.CAN-09-4254. Epub 2010 Jun 1. Cancer Res. 2010. PMID: 20516123 Free PMC article.
(V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis.
Rae J, Viros A, Hayward R, Bennett DC, Dhomen N, Longley BJ, Reis-Filho JS, Marais R. Rae J, et al. Among authors: dhomen n. J Invest Dermatol. 2012 Feb;132(2):488-91. doi: 10.1038/jid.2011.341. Epub 2011 Nov 24. J Invest Dermatol. 2012. PMID: 22113477 Free article. No abstract available.
Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53.
Viros A, Sanchez-Laorden B, Pedersen M, Furney SJ, Rae J, Hogan K, Ejiama S, Girotti MR, Cook M, Dhomen N, Marais R. Viros A, et al. Among authors: dhomen n. Nature. 2014 Jul 24;511(7510):478-482. doi: 10.1038/nature13298. Epub 2014 Jun 11. Nature. 2014. PMID: 24919155 Free PMC article.
42 results