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Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.
Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG. Phelan JE, et al. Among authors: dheda k. BMC Genomics. 2016 Feb 29;17:151. doi: 10.1186/s12864-016-2467-y. BMC Genomics. 2016. PMID: 26923687 Free PMC article.
Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study.
Dheda K, Shean K, Zumla A, Badri M, Streicher EM, Page-Shipp L, Willcox P, John MA, Reubenson G, Govindasamy D, Wong M, Padanilam X, Dziwiecki A, van Helden PD, Siwendu S, Jarand J, Menezes CN, Burns A, Victor T, Warren R, Grobusch MP, van der Walt M, Kvasnovsky C. Dheda K, et al. Lancet. 2010 May 22;375(9728):1798-807. doi: 10.1016/S0140-6736(10)60492-8. Lancet. 2010. PMID: 20488525 Free article.
Mycobacterium tuberculosis population structure determines the outcome of genetics-based second-line drug resistance testing.
Streicher EM, Bergval I, Dheda K, Böttger EC, Gey van Pittius NC, Bosman M, Coetzee G, Anthony RM, van Helden PD, Victor TC, Warren RM. Streicher EM, et al. Among authors: dheda k. Antimicrob Agents Chemother. 2012 May;56(5):2420-7. doi: 10.1128/AAC.05905-11. Epub 2012 Feb 13. Antimicrob Agents Chemother. 2012. PMID: 22330913 Free PMC article.
Drug-associated adverse events and their relationship with outcomes in patients receiving treatment for extensively drug-resistant tuberculosis in South Africa.
Shean K, Streicher E, Pieterson E, Symons G, van Zyl Smit R, Theron G, Lehloenya R, Padanilam X, Wilcox P, Victor TC, van Helden P, Grobusch MP, Warren R, Badri M, Dheda K. Shean K, et al. Among authors: dheda k. PLoS One. 2013 May 7;8(5):e63057. doi: 10.1371/journal.pone.0063057. Print 2013. PLoS One. 2013. PMID: 23667572 Free PMC article.
High frequency of resistance, lack of clinical benefit, and poor outcomes in capreomycin treated South African patients with extensively drug-resistant tuberculosis.
Pietersen E, Peter J, Streicher E, Sirgel F, Rockwood N, Mastrapa B, Te Riele J, Davids M, van Helden P, Warren R, Dheda K. Pietersen E, et al. Among authors: dheda k. PLoS One. 2015 Apr 24;10(4):e0123655. doi: 10.1371/journal.pone.0123655. eCollection 2015. PLoS One. 2015. PMID: 25909847 Free PMC article.
383 results