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Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model.
Spatz P, Steinmüller SAM, Tutov A, Poeta E, Morilleau A, Carles A, Deventer MH, Hofmann J, Stove CP, Monti B, Maurice T, Decker M. Spatz P, et al. Among authors: deventer mh. J Med Chem. 2023 May 11;66(9):6414-6435. doi: 10.1021/acs.jmedchem.3c00541. Epub 2023 Apr 26. J Med Chem. 2023. PMID: 37127287 Free PMC article.
NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?
Ametovski A, Cairns EA, Grafinger KE, Cannaert A, Deventer MH, Chen S, Wu X, Shepperson CE, Lai F, Ellison R, Gerona R, Blakey K, Kevin R, McGregor IS, Hibbs DE, Glass M, Stove C, Auwärter V, Banister SD. Ametovski A, et al. Among authors: deventer mh. ACS Chem Neurosci. 2021 Nov 3;12(21):4020-4036. doi: 10.1021/acschemneuro.1c00348. Epub 2021 Oct 22. ACS Chem Neurosci. 2021. PMID: 34676751
Structure-activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA, and ADB-P7AICA.
Sparkes E, Cairns EA, Kevin RC, Lai F, Grafinger KE, Chen S, Deventer MH, Ellison R, Boyd R, Martin LJ, McGregor IS, Gerona RR, Hibbs DE, Auwärter V, Glass M, Stove C, Banister SD. Sparkes E, et al. Among authors: deventer mh. RSC Med Chem. 2021 Oct 25;13(2):156-174. doi: 10.1039/d1md00242b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308023 Free PMC article.
Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) "Cis-On" Agonist.
Rodríguez-Soacha DA, Steinmüller SAM, Işbilir A, Fender J, Deventer MH, Ramírez YA, Tutov A, Sotriffer C, Stove CP, Lorenz K, Lohse MJ, Hislop JN, Decker M. Rodríguez-Soacha DA, et al. Among authors: deventer mh. ACS Chem Neurosci. 2022 Aug 17;13(16):2410-2435. doi: 10.1021/acschemneuro.2c00160. Epub 2022 Jul 26. ACS Chem Neurosci. 2022. PMID: 35881914
14 results