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Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors.
J Med Chem. 2024 Jan 11;67(1):572-585. doi: 10.1021/acs.jmedchem.3c01779. Epub 2023 Dec 19.
J Med Chem. 2024.
PMID: 38113354
Free PMC article.
Dissecting the Permeability of the Escherichia coli Cell Envelope to a Small Molecule Using Tailored Intensiometric Fluorescent Protein Sensors.
Kemp P, Weber W, Desczyk C, Kaufmann M, Panthel J, Wörmann T, Stein V.
Kemp P, et al. Among authors: desczyk c.
ACS Omega. 2023 Oct 11;8(42):39562-39569. doi: 10.1021/acsomega.3c05405. eCollection 2023 Oct 24.
ACS Omega. 2023.
PMID: 37901533
Free PMC article.
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Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.
Petri L, Ábrányi-Balogh P, Tímea I, Pálfy G, Perczel A, Knez D, Hrast M, Gobec M, Sosič I, Nyíri K, Vértessy BG, Jänsch N, Desczyk C, Meyer-Almes FJ, Ogris I, Golič Grdadolnik S, Iacovino LG, Binda C, Gobec S, Keserű GM.
Petri L, et al. Among authors: desczyk c.
Chembiochem. 2021 Feb 15;22(4):743-753. doi: 10.1002/cbic.202000700. Epub 2020 Nov 9.
Chembiochem. 2021.
PMID: 33030752
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Switching the Switch: Ligand Induced Disulfide Formation in HDAC8.
Jänsch N, Sugiarto WO, Muth M, Kopranovic A, Desczyk C, Ballweg M, Kirschhöfer F, Brenner-Weiss G, Meyer-Almes FJ.
Jänsch N, et al. Among authors: desczyk c.
Chemistry. 2020 Oct 15;26(58):13249-13255. doi: 10.1002/chem.202001712. Epub 2020 Sep 11.
Chemistry. 2020.
PMID: 32428298
Free PMC article.
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