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Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening.
Sci Rep. 2017 Jun 13;7(1):3424. doi: 10.1038/s41598-017-03427-z.
Sci Rep. 2017.
PMID: 28611375
Free PMC article.
Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys.
Desallais L, Bouchez C, Mouhsine H, Moreau G, Ratsimandresy R, Montes M, Do H, Quintin-Colonna F, Zagury JF.
Desallais L, et al.
Sci Rep. 2016 Jan 19;6:19549. doi: 10.1038/srep19549.
Sci Rep. 2016.
PMID: 26782790
Free PMC article.
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Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis.
Desallais L, Avouac J, Fréchet M, Elhai M, Ratsimandresy R, Montes M, Mouhsine H, Do H, Zagury JF, Allanore Y.
Desallais L, et al.
Arthritis Res Ther. 2014 Jul 24;16(4):R157. doi: 10.1186/ar4672.
Arthritis Res Ther. 2014.
PMID: 25059342
Free PMC article.
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