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Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by testing only tumour DNA in non-mucinous high-grade epithelial ovarian cancer.
Morgan RD, Burghel GJ, Flaum N, Bulman M, Smith P, Clamp AR, Hasan J, Mitchell C, Salih Z, Woodward ER, Lalloo F, Shaw J, Desai S, Crosbie EJ, Edmondson RJ, Schlecht H, Wallace AJ, Jayson GC, Evans DGR. Morgan RD, et al. Among authors: desai s. J Clin Pathol. 2023 Oct;76(10):684-689. doi: 10.1136/jcp-2022-208369. Epub 2022 Jun 23. J Clin Pathol. 2023. PMID: 35738887
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.
Nelson L, Tighe A, Golder A, Littler S, Bakker B, Moralli D, Murtuza Baker S, Donaldson IJ, Spierings DCJ, Wardenaar R, Neale B, Burghel GJ, Winter-Roach B, Edmondson R, Clamp AR, Jayson GC, Desai S, Green CM, Hayes A, Foijer F, Morgan RD, Taylor SS. Nelson L, et al. Among authors: desai s. Nat Commun. 2020 Feb 13;11(1):822. doi: 10.1038/s41467-020-14551-2. Nat Commun. 2020. PMID: 32054838 Free PMC article.
Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models.
Coulson-Gilmer C, Morgan RD, Nelson L, Barnes BM, Tighe A, Wardenaar R, Spierings DCJ, Schlecht H, Burghel GJ, Foijer F, Desai S, McGrail JC, Taylor SS. Coulson-Gilmer C, et al. Among authors: desai s. J Exp Clin Cancer Res. 2021 Oct 16;40(1):323. doi: 10.1186/s13046-021-02124-0. J Exp Clin Cancer Res. 2021. PMID: 34656146 Free PMC article.
3,753 results