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Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.
Picon S, Boulahjar R, Hoguet V, Baron M, Duplan I, Vallez E, Hennuyer N, Dumont J, Touche V, Dorchies E, Lasalle M, Descat A, Piveteau C, Biela A, Chaput L, Villoutreix BO, Lipka E, Sevin E, Culot M, Gosselet F, Lestavel S, Roussel P, Deprez-Poulain R, Leroux F, Staels B, Deprez B, Tailleux A, Charton J. Picon S, et al. Among authors: deprez b. J Med Chem. 2023 Sep 14;66(17):11732-11760. doi: 10.1021/acs.jmedchem.2c01881. Epub 2023 Aug 28. J Med Chem. 2023. PMID: 37639383
Rescue of nonsense mutations by amlexanox in human cells.
Gonzalez-Hilarion S, Beghyn T, Jia J, Debreuck N, Berte G, Mamchaoui K, Mouly V, Gruenert DC, Déprez B, Lejeune F. Gonzalez-Hilarion S, et al. Among authors: deprez b. Orphanet J Rare Dis. 2012 Aug 31;7:58. doi: 10.1186/1750-1172-7-58. Orphanet J Rare Dis. 2012. PMID: 22938201 Free PMC article.
Fenofibrate-loaded PLGA microparticles: effects on ischemic stroke.
Klose D, Laprais M, Leroux V, Siepmann F, Deprez B, Bordet R, Siepmann J. Klose D, et al. Among authors: deprez b. Eur J Pharm Sci. 2009 Apr 11;37(1):43-52. doi: 10.1016/j.ejps.2008.12.016. Epub 2009 Jan 9. Eur J Pharm Sci. 2009. PMID: 19168134
Facts, figures and trends in lead generation.
Deprez-Poulain R, Deprez B. Deprez-Poulain R, et al. Among authors: deprez b. Curr Top Med Chem. 2004;4(6):569-80. doi: 10.2174/1568026043451168. Curr Top Med Chem. 2004. PMID: 14965294 Review.
109 results