Deol KK - Search Results

1

Small-molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states.

Riepe C, Wąchalska M, Deol KK, Amaya AK, Porteus MH, Olzmann JA, Kopito RR. Riepe C, et al. Among authors: deol kk. Mol Biol Cell. 2024 Feb 1;35(2):ar15. doi: 10.1091/mbc.E23-08-0336. Epub 2023 Nov 29. Mol Biol Cell. 2024. PMID: 38019608 Free PMC article.

2

A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity.

Morris SNS, Deol KK, Lange M, Olzmann JA. Morris SNS, et al. Among authors: deol kk. Biol Open. 2022 Dec 15;11(12):bio059695. doi: 10.1242/bio.059695. Epub 2022 Dec 19. Biol Open. 2022. PMID: 36409314 Free PMC article.

3

Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.

Roberts MA, Deol KK, Mathiowetz AJ, Lange M, Leto DE, Stevenson J, Hashemi SH, Morgens DW, Easter E, Heydari K, Nalls MA, Bassik MC, Kampmann M, Kopito RR, Faghri F, Olzmann JA. Roberts MA, et al. Among authors: deol kk. Dev Cell. 2023 Sep 25;58(18):1782-1800.e10. doi: 10.1016/j.devcel.2023.07.001. Epub 2023 Jul 25. Dev Cell. 2023. PMID: 37494933 Free article.

4

Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis.

Hendricks JM, Doubravsky CE, Wehri E, Li Z, Roberts MA, Deol KK, Lange M, Lasheras-Otero I, Momper JD, Dixon SJ, Bersuker K, Schaletzky J, Olzmann JA. Hendricks JM, et al. Among authors: deol kk. Cell Chem Biol. 2023 Sep 21;30(9):1090-1103.e7. doi: 10.1016/j.chembiol.2023.04.007. Epub 2023 May 12. Cell Chem Biol. 2023. PMID: 37178691

5

Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states.

Riepe C, Wąchalska M, Deol KK, Amaya AK, Porteus MH, Olzmann JA, Kopito RR. Riepe C, et al. Among authors: deol kk. bioRxiv [Preprint]. 2023 Sep 16:2023.09.15.556420. doi: 10.1101/2023.09.15.556420. bioRxiv. 2023. PMID: 37745470 Free PMC article. Updated. Preprint.

6

Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.

Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. Li Z, et al. Among authors: deol kk. Nat Chem Biol. 2022 Jul;18(7):751-761. doi: 10.1038/s41589-022-01033-3. Epub 2022 May 30. Nat Chem Biol. 2022. PMID: 35637349 Free PMC article.

7

A cryptic K48 ubiquitin chain binding site on UCH37 is required for its role in proteasomal degradation.

Du J, Babik S, Li Y, Deol KK, Eyles SJ, Fejzo J, Tonelli M, Strieter E. Du J, et al. Among authors: deol kk. Elife. 2022 Apr 22;11:e76100. doi: 10.7554/eLife.76100. Elife. 2022. PMID: 35451368 Free PMC article.

8

Optimized protocol for the identification of lipid droplet proteomes using proximity labeling proteomics in cultured human cells.

Peterson CWH, Deol KK, To M, Olzmann JA. Peterson CWH, et al. Among authors: deol kk. STAR Protoc. 2021 Jun 5;2(2):100579. doi: 10.1016/j.xpro.2021.100579. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34151299 Free PMC article.

9

The ubiquitin proteoform problem.

Deol KK, Strieter ER. Deol KK, et al. Curr Opin Chem Biol. 2021 Aug;63:95-104. doi: 10.1016/j.cbpa.2021.02.015. Epub 2021 Apr 1. Curr Opin Chem Biol. 2021. PMID: 33813043 Free PMC article. Review.

10

Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation.

Deol KK, Crowe SO, Du J, Bisbee HA, Guenette RG, Strieter ER. Deol KK, et al. Mol Cell. 2020 Dec 3;80(5):796-809.e9. doi: 10.1016/j.molcel.2020.10.017. Epub 2020 Nov 5. Mol Cell. 2020. PMID: 33156996 Free PMC article.

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