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Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.
Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D. Dentice M, et al. Cell Metab. 2014 Dec 2;20(6):1038-48. doi: 10.1016/j.cmet.2014.10.009. Epub 2014 Nov 13. Cell Metab. 2014. PMID: 25456740 Free PMC article.
Pharmacological folding chaperones act as allosteric ligands of Frizzled4.
Generoso SF, Giustiniano M, La Regina G, Bottone S, Passacantilli S, Di Maro S, Cassese H, Bruno A, Mallardo M, Dentice M, Silvestri R, Marinelli L, Sarnataro D, Bonatti S, Novellino E, Stornaiuolo M. Generoso SF, et al. Among authors: dentice m. Nat Chem Biol. 2015 Apr;11(4):280-6. doi: 10.1038/nchembio.1770. Epub 2015 Mar 9. Nat Chem Biol. 2015. PMID: 25751279
Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.
Di Girolamo D, Ambrosio R, De Stefano MA, Mancino G, Porcelli T, Luongo C, Di Cicco E, Scalia G, Vecchio LD, Colao A, Dlugosz AA, Missero C, Salvatore D, Dentice M. Di Girolamo D, et al. Among authors: dentice m. J Clin Invest. 2016 Jun 1;126(6):2308-20. doi: 10.1172/JCI84465. Epub 2016 May 9. J Clin Invest. 2016. PMID: 27159391 Free PMC article.
83 results