Denny PW - Search Results

1

An investigation of the antileishmanial properties of semi-synthetic saponins.

Anderson O, Beckett J, Briggs CC, Natrass LA, Cranston CF, Wilkinson EJ, Owen JH, Mir Williams R, Loukaidis A, Bouillon ME, Pritchard D, Lahmann M, Baird MS, Denny PW. Anderson O, et al. Among authors: denny pw. RSC Med Chem. 2020 Jun 9;11(7):833-842. doi: 10.1039/d0md00123f. eCollection 2020 Jul 1. RSC Med Chem. 2020. PMID: 33479679 Free PMC article.

2

Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa.

Chadbourne FL, Raleigh C, Ali HZ, Denny PW, Cobb SL. Chadbourne FL, et al. Among authors: denny pw. J Pept Sci. 2011 Nov;17(11):751-5. doi: 10.1002/psc.1398. Epub 2011 Aug 1. J Pept Sci. 2011. PMID: 21805542

3

Mining for natural product antileishmanials in a fungal extract library.

Mbekeani AJ, Jones RS, Bassas Llorens M, Elliot J, Regnault C, Barrett MP, Steele J, Kebede B, Wrigley SK, Evans L, Denny PW. Mbekeani AJ, et al. Among authors: denny pw. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:118-128. doi: 10.1016/j.ijpddr.2019.05.003. Epub 2019 Jun 11. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31208892 Free PMC article.

4

Clemastine/tamoxifen hybrids as easily accessible antileishmanial drug leads.

Agostino VS, Buerdsell ML, Uliana SRB, Denny PW, Coelho AC, Steel PG. Agostino VS, et al. Among authors: denny pw. Org Biomol Chem. 2024 Feb 28;22(9):1812-1820. doi: 10.1039/d3ob02091f. Org Biomol Chem. 2024. PMID: 38328995

5

The protozoan inositol phosphorylceramide synthase: a novel drug target that defines a new class of sphingolipid synthase.

Denny PW, Shams-Eldin H, Price HP, Smith DF, Schwarz RT. Denny PW, et al. J Biol Chem. 2006 Sep 22;281(38):28200-9. doi: 10.1074/jbc.M600796200. Epub 2006 Jul 22. J Biol Chem. 2006. PMID: 16861742 Free PMC article.

6

Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing.

Trmčić M, Chadbourne FL, Brear PM, Denny PW, Cobb SL, Hodgson DR. Trmčić M, et al. Among authors: denny pw. Org Biomol Chem. 2013 Apr 28;11(16):2660-75. doi: 10.1039/c3ob27448a. Org Biomol Chem. 2013. PMID: 23467665

7

Investigating the anti-leishmanial effects of linear peptoids.

Eggimann GA, Bolt HL, Denny PW, Cobb SL. Eggimann GA, et al. Among authors: denny pw. ChemMedChem. 2015 Feb;10(2):233-7. doi: 10.1002/cmdc.201402416. Epub 2014 Dec 15. ChemMedChem. 2015. PMID: 25512204

8

Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art.

Charlton RL, Rossi-Bergmann B, Denny PW, Steel PG. Charlton RL, et al. Among authors: denny pw. Parasitology. 2018 Feb;145(2):219-236. doi: 10.1017/S0031182017000993. Epub 2017 Aug 14. Parasitology. 2018. PMID: 28805165 Free PMC article. Review.

9

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform.

Norcliffe JL, Mina JG, Alvarez E, Cantizani J, de Dios-Anton F, Colmenarejo G, Valle SG, Marco M, Fiandor JM, Martin JJ, Steel PG, Denny PW. Norcliffe JL, et al. Among authors: denny pw. Sci Rep. 2018 Mar 2;8(1):3938. doi: 10.1038/s41598-018-22063-9. Sci Rep. 2018. PMID: 29500420 Free PMC article.

10

The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity.

Pinneh EC, Mina JG, Stark MJR, Lindell SD, Luemmen P, Knight MR, Steel PG, Denny PW. Pinneh EC, et al. Among authors: denny pw. Sci Rep. 2019 May 30;9(1):8083. doi: 10.1038/s41598-019-44544-1. Sci Rep. 2019. PMID: 31147620 Free PMC article.

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