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Combined Focused Next-Generation Sequencing Assays to Guide Precision Oncology in Solid Tumors: A Retrospective Analysis from an Institutional Molecular Tumor Board.
Tarawneh TS, Rodepeter FR, Teply-Szymanski J, Ross P, Koch V, Thölken C, Schäfer JA, Gremke N, Mack HID, Gold J, Riera-Knorrenschild J, Wilhelm C, Rinke A, Middeke M, Klemmer A, Romey M, Hattesohl A, Jesinghaus M, Görg C, Figiel J, Chung HR, Wündisch T, Neubauer A, Denkert C, Mack EKM. Tarawneh TS, et al. Among authors: denkert c. Cancers (Basel). 2022 Sep 12;14(18):4430. doi: 10.3390/cancers14184430. Cancers (Basel). 2022. PMID: 36139590 Free PMC article.
Characteristics and Clinical Outcome of Breast Cancer Patients with Asymptomatic Brain Metastases.
Laakmann E, Witzel I, Neunhöffer T, Weide R, Schmidt M, Park-Simon TW, Möbus V, Mundhenke C, Polasik A, Lübbe K, Hesse T, Riecke K, Thill M, Fasching PA, Denkert C, Fehm T, Nekljudova V, Rey J, Loibl S, Müller V. Laakmann E, et al. Among authors: denkert c. Cancers (Basel). 2020 Sep 28;12(10):2787. doi: 10.3390/cancers12102787. Cancers (Basel). 2020. PMID: 32998430 Free PMC article.
Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Study. A Report on Behalf of the International Immuno-Oncology Biomarker Working Group.
Van Bockstal MR, Cooks M, Nederlof I, Brinkhuis M, Dutman A, Koopmans M, Kooreman L, van der Vegt B, Verhoog L, Vreuls C, Westenend P, Kok M, van Diest PJ, Nauwelaers I, Laudus N, Denkert C, Rimm D, Siziopikou KP, Ely S, Zardavas D, Roberts M, Floris G, Hartman J, Acs B, Peeters D, Bartlett JMS, Dequeker E, Salgado R, Giudici F, Michiels S, Horlings H, van Deurzen CHM. Van Bockstal MR, et al. Among authors: denkert c. Cancers (Basel). 2021 Sep 29;13(19):4910. doi: 10.3390/cancers13194910. Cancers (Basel). 2021. PMID: 34638394 Free PMC article.
Neuroendocrine Differentiation in Conventional Colorectal Adenocarcinomas: Incidental Finding or Prognostic Biomarker?
Konukiewitz B, Kasajima A, Schmitt M, Schwamborn K, Groll T, Schicktanz F, Delbridge C, Schütze LM, Wilhelm D, Lang C, Lange S, Foersch S, Jank P, Steiger K, Werder AV, Denkert C, Weichert W, Klöppel G, Jesinghaus M. Konukiewitz B, et al. Among authors: denkert c. Cancers (Basel). 2021 Oct 12;13(20):5111. doi: 10.3390/cancers13205111. Cancers (Basel). 2021. PMID: 34680258 Free PMC article.
Loss of SATB2 Occurs More Frequently Than CDX2 Loss in Colorectal Carcinoma and Identifies Particularly Aggressive Cancers in High-Risk Subgroups.
Schmitt M, Silva M, Konukiewitz B, Lang C, Steiger K, Halfter K, Engel J, Jank P, Pfarr N, Wilhelm D, Foersch S, Denkert C, Tschurtschenthaler M, Weichert W, Jesinghaus M. Schmitt M, et al. Among authors: denkert c. Cancers (Basel). 2021 Dec 7;13(24):6177. doi: 10.3390/cancers13246177. Cancers (Basel). 2021. PMID: 34944797 Free PMC article.
Homologous Recombination Deficiency as an Ovarian Cancer Biomarker in a Real-World Cohort: Validation of Decentralized Genomic Profiling.
Denkert C, Romey M, Swedlund B, Hattesohl A, Teply-Szymanski J, Kommoss S, Kaiser K, Staebler A, du Bois A, Grass A, Knappmeyer C, Heitz F, Solimeno C, Ebel T, Harter P, Marmé F, Jank P, Gaiser T, Neff C, Wagner U, Timms KM, Rodepeter F. Denkert C, et al. J Mol Diagn. 2022 Dec;24(12):1254-1263. doi: 10.1016/j.jmoldx.2022.09.004. Epub 2022 Sep 30. J Mol Diagn. 2022. PMID: 36191839 Free article.
Low Expression of RGS2 Promotes Poor Prognosis in High-Grade Serous Ovarian Cancer.
Ihlow J, Monjé N, Hoffmann I, Bischoff P, Sinn BV, Schmitt WD, Kunze CA, Darb-Esfahani S, Kulbe H, Braicu EI, Sehouli J, Denkert C, Horst D, Taube ET. Ihlow J, et al. Among authors: denkert c. Cancers (Basel). 2022 Sep 23;14(19):4620. doi: 10.3390/cancers14194620. Cancers (Basel). 2022. PMID: 36230542 Free PMC article.
High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrine carcinomas from conventional adenocarcinomas with diffuse expression of synaptophysin.
Litmeyer AS, Konukiewitz B, Kasajima A, Foersch S, Schicktanz F, Schmitt M, Kellers F, Grass A, Jank P, Lehman B, Gress TM, Rinke A, Bartsch DK, Denkert C, Weichert W, Klöppel G, Jesinghaus M. Litmeyer AS, et al. Among authors: denkert c. J Pathol Clin Res. 2023 Nov;9(6):498-509. doi: 10.1002/cjp2.339. Epub 2023 Aug 22. J Pathol Clin Res. 2023. PMID: 37608427 Free PMC article.
Two Germline Pathogenic Variants in Cancer Susceptibility Genes and Their Null Implication in Breast Cancer Pathogenesis: The Importance of Tumoral Homologous Recombination Deficiency Testing.
Rezqallah A, Torres-Esquius S, Llop-Guevara A, Cruellas M, Martinez MT, Romey M, Denkert C, Serra V, Chirivella I, Balmaña J. Rezqallah A, et al. Among authors: denkert c. JCO Precis Oncol. 2024 Mar;8:e2300446. doi: 10.1200/PO.23.00446. JCO Precis Oncol. 2024. PMID: 38513169
477 results