Mirk/dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288.
Zou Y, Ewton DZ, Deng X, Mercer SE, Friedman E.
Zou Y, et al. Among authors: deng x.
J Biol Chem. 2004 Jun 25;279(26):27790-8. doi: 10.1074/jbc.M403042200. Epub 2004 Apr 9.
J Biol Chem. 2004.
PMID: 15075324
Free article.
Destabilization was confirmed by induction of a stable Mirk transfectant of Mv1Lu cells, which blocked cell migration (Zou, Y., Lim, S., Lee, K., Deng, X., and Friedman, E. (2003) J. Biol. Chem. 278, 49573-49581), and caused a decrease in the half-life of endogenous …
Destabilization was confirmed by induction of a stable Mirk transfectant of Mv1Lu cells, which blocked cell migration (Zou, Y., Lim, S., Lee …