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Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.
He R, Hou S, Liu C, Zhang A, Bai Q, Han M, Yang Y, Wei G, Shen T, Yang X, Xu L, Chen X, Hao Y, Wang P, Zhu C, Ou J, Liang H, Ni T, Zhang X, Zhou X, Deng K, Chen Y, Luo Y, Xu J, Qi H, Wu Y, Ye L. He R, et al. Among authors: deng k. Nature. 2016 Aug 2;537(7620):412-428. doi: 10.1038/nature19317. Nature. 2016. PMID: 27501245
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF. Deng K, et al. Nature. 2015 Jan 15;517(7534):381-5. doi: 10.1038/nature14053. Epub 2015 Jan 7. Nature. 2015. PMID: 25561180 Free PMC article.
Erratum: Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection.
He R, Hou S, Liu C, Zhang A, Bai Q, Han M, Yang Y, Wei G, Shen T, Yang X, Xu L, Chen X, Hao Y, Wang P, Zhu C, Ou J, Liang H, Ni T, Zhang X, Zhou X, Deng K, Chen Y, Luo Y, Xu J, Qi H, Wu Y, Ye L. He R, et al. Among authors: deng k. Nature. 2016 Oct 19;540(7633):470. doi: 10.1038/nature20107. Nature. 2016. PMID: 27762350 No abstract available.
Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor.
Chen X, Li R, Pan Z, Qian C, Yang Y, You R, Zhao J, Liu P, Gao L, Li Z, Huang Q, Xu L, Tang J, Tian Q, Yao W, Hu L, Yan X, Zhou X, Wu Y, Deng K, Zhang Z, Qian Z, Chen Y, Ye L. Chen X, et al. Among authors: deng k. Cell Mol Immunol. 2020 Jun;17(6):647-649. doi: 10.1038/s41423-020-0426-7. Epub 2020 Apr 20. Cell Mol Immunol. 2020. PMID: 32313207 Free PMC article. No abstract available.
Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19.
Chen X, Pan Z, Yue S, Yu F, Zhang J, Yang Y, Li R, Liu B, Yang X, Gao L, Li Z, Lin Y, Huang Q, Xu L, Tang J, Hu L, Zhao J, Liu P, Zhang G, Chen Y, Deng K, Ye L. Chen X, et al. Among authors: deng k. Signal Transduct Target Ther. 2020 Sep 2;5(1):180. doi: 10.1038/s41392-020-00301-9. Signal Transduct Target Ther. 2020. PMID: 32879307 Free PMC article.
Heterogeneity of HIV-1 latent reservoirs.
Zhao JC, Deng K. Zhao JC, et al. Among authors: deng k. Chin Med J (Engl). 2020 Dec 5;133(23):2867-2873. doi: 10.1097/CM9.0000000000001085. Chin Med J (Engl). 2020. PMID: 33273337 Free PMC article.
A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD.
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L. Wang X, et al. Among authors: deng k. Signal Transduct Target Ther. 2022 Apr 5;7(1):114. doi: 10.1038/s41392-022-00954-8. Signal Transduct Target Ther. 2022. PMID: 35383141 Free PMC article.
HIV: Early treatment may not be early enough.
Deng K, Siliciano RF. Deng K, et al. Nature. 2014 Aug 7;512(7512):35-6. doi: 10.1038/nature13647. Epub 2014 Jul 20. Nature. 2014. PMID: 25043038 No abstract available.
2,093 results