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The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, Henske EP, Haigis MC, Cantley LC, Stephanopoulos G, Yu J, Blenis J. Csibi A, et al. Among authors: dempsey jm. Cell. 2021 Apr 15;184(8):2256. doi: 10.1016/j.cell.2021.03.059. Cell. 2021. PMID: 33861966 Free article. No abstract available.
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.
Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure NE, Blackwell TK, Yu JJ, Rabinowitz JD, Cantley LC, Blenis J. Lee G, et al. Among authors: dempsey jm. Cell. 2017 Dec 14;171(7):1545-1558.e18. doi: 10.1016/j.cell.2017.10.037. Epub 2017 Nov 16. Cell. 2017. PMID: 29153836 Free PMC article.
Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic.
Work EM, Ferraudi G, Kiefer L, Liu G, Grigalunas M, Bhardwaj A, Kaur R, Dempsey JM, Wüstner D, Helquist P, Wiest O. Work EM, et al. Among authors: dempsey jm. J Org Chem. 2021 Jan 15;86(2):1612-1621. doi: 10.1021/acs.joc.0c02460. Epub 2020 Dec 28. J Org Chem. 2021. PMID: 33369429 Free PMC article.
17 results