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Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability.
Gaggioli V, Lo CSY, Reverón-Gómez N, Jasencakova Z, Domenech H, Nguyen H, Sidoli S, Tvardovskiy A, Uruci S, Slotman JA, Chai Y, Gonçalves JGSCS, Manolika EM, Jensen ON, Wheeler D, Sridharan S, Chakrabarty S, Demmers J, Kanaar R, Groth A, Taneja N. Gaggioli V, et al. Among authors: demmers j. Nat Cell Biol. 2023 Jul;25(7):1017-1032. doi: 10.1038/s41556-023-01167-z. Epub 2023 Jul 6. Nat Cell Biol. 2023. PMID: 37414849 Free PMC article.
SMARCAD1-mediated active replication fork stability maintains genome integrity.
Lo CSY, van Toorn M, Gaggioli V, Paes Dias M, Zhu Y, Manolika EM, Zhao W, van der Does M, Mukherjee C, G S C Souto Gonçalves J, van Royen ME, French PJ, Demmers J, Smal I, Lans H, Wheeler D, Jonkers J, Chaudhuri AR, Marteijn JA, Taneja N. Lo CSY, et al. Among authors: demmers j. Sci Adv. 2021 May 5;7(19):eabe7804. doi: 10.1126/sciadv.abe7804. Print 2021 May. Sci Adv. 2021. PMID: 33952518 Free PMC article.
On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation.
van den Tempel N, Zelensky AN, Odijk H, Laffeber C, Schmidt CK, Brandsma I, Demmers J, Krawczyk PM, Kanaar R. van den Tempel N, et al. Among authors: demmers j. Cancers (Basel). 2019 Jan 15;11(1):97. doi: 10.3390/cancers11010097. Cancers (Basel). 2019. PMID: 30650591 Free PMC article.
Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.
van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J. van der Pluijm I, et al. Among authors: demmers ja. Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150. Cardiovasc Res. 2018. PMID: 29931197 Free PMC article.
210 results