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Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model.
Tallon C, Bell BJ, Malvankar MM, Deme P, Nogueras-Ortiz C, Eren E, Thomas AG, Hollinger KR, Pal A, Mustapic M, Huang M, Coleman K, Joe TR, Rais R, Haughey NJ, Kapogiannis D, Slusher BS. Tallon C, et al. Among authors: deme p. Transl Neurodegener. 2023 Dec 4;12(1):56. doi: 10.1186/s40035-023-00383-9. Transl Neurodegener. 2023. PMID: 38049923 Free PMC article.
Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
Yoo SW, Waheed AA, Deme P, Tohumeken S, Rais R, Smith MD, DeMarino C, Calabresi PA, Kashanchi F, Freed EO, Slusher BS, Haughey NJ. Yoo SW, et al. Among authors: deme p. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2219543120. doi: 10.1073/pnas.2219543120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406092 Free PMC article.
Lipidomic characterization of extracellular vesicles in human serum.
Chen S, Datta-Chaudhuri A, Deme P, Dickens A, Dastgheyb R, Bhargava P, Bi H, Haughey NJ. Chen S, et al. Among authors: deme p. J Circ Biomark. 2019 Sep 30;8:1849454419879848. doi: 10.1177/1849454419879848. eCollection 2019 Jan-Dec. J Circ Biomark. 2019. PMID: 31632506 Free PMC article.
39 results