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Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
J Exp Med. 2021 Jul 5;218(7):e20210223. doi: 10.1084/jem.20210223. Epub 2021 May 25.
J Exp Med. 2021.
PMID: 34032859
Free PMC article.
Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation.
Verovskaya EV, Dellorusso PV, Passegué E.
Verovskaya EV, et al. Among authors: dellorusso pv.
Trends Mol Med. 2019 Jun;25(6):494-515. doi: 10.1016/j.molmed.2019.04.006. Epub 2019 May 17.
Trends Mol Med. 2019.
PMID: 31109796
Free PMC article.
Review.
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Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis.
Yamashita M, Dellorusso PV, Olson OC, Passegué E.
Yamashita M, et al. Among authors: dellorusso pv.
Nat Rev Cancer. 2020 Jul;20(7):365-382. doi: 10.1038/s41568-020-0260-3. Epub 2020 May 15.
Nat Rev Cancer. 2020.
PMID: 32415283
Free PMC article.
Review.
Item in Clipboard
Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.
Mitchell CA, Verovskaya EV, Calero-Nieto FJ, Olson OC, Swann JW, Wang X, Hérault A, Dellorusso PV, Zhang SY, Svendsen AF, Pietras EM, Bakker ST, Ho TT, Göttgens B, Passegué E.
Mitchell CA, et al. Among authors: dellorusso pv.
Nat Cell Biol. 2023 Jan;25(1):30-41. doi: 10.1038/s41556-022-01053-0. Epub 2023 Jan 17.
Nat Cell Biol. 2023.
PMID: 36650381
Free PMC article.
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Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells.
Dellorusso PV, Proven MA, Calero-Nieto FJ, Wang X, Mitchell CA, Hartmann F, Amouzgar M, Favaro P, DeVilbiss A, Swann JW, Ho TT, Zhao Z, Bendall SC, Morrison S, Göttgens B, Passegué E.
Dellorusso PV, et al.
bioRxiv [Preprint]. 2023 Aug 19:2023.08.17.553736. doi: 10.1101/2023.08.17.553736.
bioRxiv. 2023.
PMID: 37645930
Free PMC article.
Preprint.
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Maternal IL-10 restricts fetal emergency myelopoiesis.
Collins A, Swann JW, Proven MA, Patel CM, Mitchell CA, Kasbekar M, Dellorusso PV, Passegué E.
Collins A, et al. Among authors: dellorusso pv.
bioRxiv [Preprint]. 2023 Sep 13:2023.09.13.557548. doi: 10.1101/2023.09.13.557548.
bioRxiv. 2023.
PMID: 37745377
Free PMC article.
Updated.
Preprint.
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Maternal inflammation regulates fetal emergency myelopoiesis.
Collins A, Swann JW, Proven MA, Patel CM, Mitchell CA, Kasbekar M, Dellorusso PV, Passegué E.
Collins A, et al. Among authors: dellorusso pv.
Cell. 2024 Mar 14;187(6):1402-1421.e21. doi: 10.1016/j.cell.2024.02.002. Epub 2024 Feb 29.
Cell. 2024.
PMID: 38428422
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Depletion of the Shwachman-Diamond syndrome gene product, SBDS, leads to growth inhibition and increased expression of OPG and VEGF-A.
Nihrane A, Sezgin G, Dsilva S, Dellorusso P, Yamamoto K, Ellis SR, Liu JM.
Nihrane A, et al.
Blood Cells Mol Dis. 2009 Jan-Feb;42(1):85-91. doi: 10.1016/j.bcmd.2008.09.004. Epub 2008 Nov 17.
Blood Cells Mol Dis. 2009.
PMID: 19014892
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