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Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.
Mitchell CA, Verovskaya EV, Calero-Nieto FJ, Olson OC, Swann JW, Wang X, Hérault A, Dellorusso PV, Zhang SY, Svendsen AF, Pietras EM, Bakker ST, Ho TT, Göttgens B, Passegué E. Mitchell CA, et al. Among authors: dellorusso pv. Nat Cell Biol. 2023 Jan;25(1):30-41. doi: 10.1038/s41556-022-01053-0. Epub 2023 Jan 17. Nat Cell Biol. 2023. PMID: 36650381 Free PMC article.
Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells.
Dellorusso PV, Proven MA, Calero-Nieto FJ, Wang X, Mitchell CA, Hartmann F, Amouzgar M, Favaro P, DeVilbiss A, Swann JW, Ho TT, Zhao Z, Bendall SC, Morrison S, Göttgens B, Passegué E. Dellorusso PV, et al. bioRxiv [Preprint]. 2023 Aug 19:2023.08.17.553736. doi: 10.1101/2023.08.17.553736. bioRxiv. 2023. PMID: 37645930 Free PMC article. Preprint.
Maternal IL-10 restricts fetal emergency myelopoiesis.
Collins A, Swann JW, Proven MA, Patel CM, Mitchell CA, Kasbekar M, Dellorusso PV, Passegué E. Collins A, et al. Among authors: dellorusso pv. bioRxiv [Preprint]. 2023 Sep 13:2023.09.13.557548. doi: 10.1101/2023.09.13.557548. bioRxiv. 2023. PMID: 37745377 Free PMC article. Updated. Preprint.
Maternal inflammation regulates fetal emergency myelopoiesis.
Collins A, Swann JW, Proven MA, Patel CM, Mitchell CA, Kasbekar M, Dellorusso PV, Passegué E. Collins A, et al. Among authors: dellorusso pv. Cell. 2024 Mar 14;187(6):1402-1421.e21. doi: 10.1016/j.cell.2024.02.002. Epub 2024 Feb 29. Cell. 2024. PMID: 38428422