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VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes.
Calin M, Stan D, Schlesinger M, Simion V, Deleanu M, Constantinescu CA, Gan AM, Pirvulescu MM, Butoi E, Manduteanu I, Bota M, Enachescu M, Borsig L, Bendas G, Simionescu M. Calin M, et al. Among authors: deleanu m. Eur J Pharm Biopharm. 2015 Jan;89:18-29. doi: 10.1016/j.ejpb.2014.11.016. Epub 2014 Nov 28. Eur J Pharm Biopharm. 2015. PMID: 25438248 Free article.
Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells.
Simion V, Stan D, Constantinescu CA, Deleanu M, Dragan E, Tucureanu MM, Gan AM, Butoi E, Constantin A, Manduteanu I, Simionescu M, Calin M. Simion V, et al. Among authors: deleanu m. J Pharm Pharmacol. 2016 Feb;68(2):195-207. doi: 10.1111/jphp.12513. Epub 2016 Jan 8. J Pharm Pharmacol. 2016. PMID: 26748549
Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients.
Carnuta MG, Stancu CS, Toma L, Sanda GM, Niculescu LS, Deleanu M, Popescu AC, Popescu MR, Vlad A, Dimulescu DR, Simionescu M, Sima AV. Carnuta MG, et al. Among authors: deleanu m. Sci Rep. 2017 Aug 4;7(1):7295. doi: 10.1038/s41598-017-07821-5. Sci Rep. 2017. PMID: 28779156 Free PMC article.
58 results