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Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis.
Peikert K, Federti E, Matte A, Constantin G, Pietronigro EC, Fabene PF, Defilippi P, Turco E, Del Gallo F, Pucci P, Amoresano A, Illiano A, Cozzolino F, Monti M, Garello F, Terreno E, Alper SL, Glaß H, Pelzl L, Akgün K, Ziemssen T, Ordemann R, Lang F, Brunati AM, Tibaldi E, Andolfo I, Iolascon A, Bertini G, Buffelli M, Zancanaro C, Lorenzetto E, Siciliano A, Bonifacio M, Danek A, Walker RH, Hermann A, De Franceschi L. Peikert K, et al. Among authors: defilippi p. Acta Neuropathol Commun. 2021 May 3;9(1):81. doi: 10.1186/s40478-021-01181-y. Acta Neuropathol Commun. 2021. PMID: 33941276 Free PMC article.
Mapping of p140Cap phosphorylation sites: the EPLYA and EGLYA motifs have a key role in tyrosine phosphorylation and Csk binding, and are substrates of the Abl kinase.
Repetto D, Aramu S, Boeri Erba E, Sharma N, Grasso S, Russo I, Jensen ON, Cabodi S, Turco E, Di Stefano P, Defilippi P. Repetto D, et al. Among authors: defilippi p. PLoS One. 2013;8(1):e54931. doi: 10.1371/journal.pone.0054931. Epub 2013 Jan 31. PLoS One. 2013. PMID: 23383002 Free PMC article.
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.
Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P. Cabodi S, et al. Among authors: defilippi p. Cancer Res. 2006 May 1;66(9):4672-80. doi: 10.1158/0008-5472.CAN-05-2909. Cancer Res. 2006. PMID: 16651418
p130Cas is an essential transducer element in ErbB2 transformation.
Cabodi S, Tinnirello A, Bisaro B, Tornillo G, del Pilar Camacho-Leal M, Forni G, Cojoca R, Iezzi M, Amici A, Montani M, Eva A, Di Stefano P, Muthuswamy SK, Tarone G, Turco E, Defilippi P. Cabodi S, et al. Among authors: defilippi p. FASEB J. 2010 Oct;24(10):3796-808. doi: 10.1096/fj.10-157347. Epub 2010 May 26. FASEB J. 2010. PMID: 20505116
144 results