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Neuronal impact of patient-specific aberrant NRXN1α splicing.
Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJM, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, Halpern M, Deikus G, Shah H, Fitzgerald M, Ladran I, Gochman P, Rapoport J, Tsankova NM, McCullumsmith R, Hoffman GE, Sebra R, Fang G, Brennand KJ. Flaherty E, et al. Among authors: deans pjm. Nat Genet. 2019 Dec;51(12):1679-1690. doi: 10.1038/s41588-019-0539-z. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784728 Free PMC article.
Synergistic effects of common schizophrenia risk variants.
Schrode N, Ho SM, Yamamuro K, Dobbyn A, Huckins L, Matos MR, Cheng E, Deans PJM, Flaherty E, Barretto N, Topol A, Alganem K, Abadali S, Gregory J, Hoelzli E, Phatnani H, Singh V, Girish D, Aronow B, Mccullumsmith R, Hoffman GE, Stahl EA, Morishita H, Sklar P, Brennand KJ. Schrode N, et al. Among authors: deans pjm. Nat Genet. 2019 Oct;51(10):1475-1485. doi: 10.1038/s41588-019-0497-5. Epub 2019 Sep 23. Nat Genet. 2019. PMID: 31548722 Free PMC article.
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, Iwasawa K, Crary J, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Among authors: deans pjm. bioRxiv [Preprint]. 2020 Sep 21:2020.09.20.300574. doi: 10.1101/2020.09.20.300574. bioRxiv. 2020. PMID: 32995783 Free PMC article. Updated. Preprint.
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Among authors: deans pjm. Stem Cell Reports. 2021 Mar 9;16(3):505-518. doi: 10.1016/j.stemcr.2021.02.010. Epub 2021 Feb 13. Stem Cell Reports. 2021. PMID: 33636110 Free PMC article.
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.
Seah C, Breen MS, Rusielewicz T, Bader HN, Xu C, Hunter CJ, McCarthy B, Deans PJM, Chattopadhyay M, Goldberg J, Desarnaud F, Makotkine I, Flory JD, Bierer LM, Staniskyte M; NYSCF Global Stem Cell Array® Team; Noggle SA, Huckins LM, Paull D, Brennand KJ, Yehuda R. Seah C, et al. Among authors: deans pjm. Nat Neurosci. 2022 Nov;25(11):1434-1445. doi: 10.1038/s41593-022-01161-y. Epub 2022 Oct 20. Nat Neurosci. 2022. PMID: 36266471 Free PMC article.
Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells.
Bhat A, Irizar H, Couch ACM, Raval P, Duarte RRR, Dutan Polit L, Hanger B, Powell T, Deans PJM, Shum C, Nagy R, McAlonan G, Iyegbe CO, Price J, Bramon E, Bhattacharyya S, Vernon AC, Srivastava DP. Bhat A, et al. Among authors: deans pjm. Brain Behav Immun. 2022 Oct;105:82-97. doi: 10.1016/j.bbi.2022.06.010. Epub 2022 Jun 16. Brain Behav Immun. 2022. PMID: 35716830 Free PMC article.
12 results