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Evolution of a Catalytic Mechanism.
Rauwerdink A, Lunzer M, Devamani T, Jones B, Mooney J, Zhang ZJ, Xu JH, Kazlauskas RJ, Dean AM. Rauwerdink A, et al. Among authors: dean am. Mol Biol Evol. 2016 Apr;33(4):971-9. doi: 10.1093/molbev/msv338. Epub 2015 Dec 16. Mol Biol Evol. 2016. PMID: 26681154 Free PMC article.
Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases.
Devamani T, Rauwerdink AM, Lunzer M, Jones BJ, Mooney JL, Tan MA, Zhang ZJ, Xu JH, Dean AM, Kazlauskas RJ. Devamani T, et al. Among authors: dean am. J Am Chem Soc. 2016 Jan 27;138(3):1046-56. doi: 10.1021/jacs.5b12209. Epub 2016 Jan 15. J Am Chem Soc. 2016. PMID: 26736133 Free PMC article.
Pervasive cryptic epistasis in molecular evolution.
Lunzer M, Golding GB, Dean AM. Lunzer M, et al. Among authors: dean am. PLoS Genet. 2010 Oct 21;6(10):e1001162. doi: 10.1371/journal.pgen.1001162. PLoS Genet. 2010. PMID: 20975933 Free PMC article.
An empirical test of the concomitantly variable codon hypothesis.
Merlo LM, Lunzer M, Dean AM. Merlo LM, et al. Among authors: dean am. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10938-43. doi: 10.1073/pnas.0701900104. Epub 2007 Jun 19. Proc Natl Acad Sci U S A. 2007. PMID: 17578921 Free PMC article.
Direct demonstration of an adaptive constraint.
Miller SP, Lunzer M, Dean AM. Miller SP, et al. Among authors: dean am. Science. 2006 Oct 20;314(5798):458-61. doi: 10.1126/science.1133479. Science. 2006. PMID: 17053145
Adaptive Landscapes in the Age of Synthetic Biology.
Yi X, Dean AM. Yi X, et al. Among authors: dean am. Mol Biol Evol. 2019 May 1;36(5):890-907. doi: 10.1093/molbev/msz004. Mol Biol Evol. 2019. PMID: 30657938 Free PMC article. Review.
The future of molecular evolution.
Dean AM. Dean AM. EMBO Rep. 2010 Jun;11(6):409. doi: 10.1038/embor.2010.78. EMBO Rep. 2010. PMID: 20514039 Free PMC article.
122 results