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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pede… See abstract for full author list ➔ Wray NR, et al. Among authors: depaulo jr. Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3. Epub 2018 Apr 26. Nat Genet. 2018. PMID: 29700475 Free PMC article.
Are you recognizing depression in your patients?
Simpson SG, DePaulo JR Jr. Simpson SG, et al. Among authors: depaulo jr jr. Postgrad Med. 1993 Sep 1;94(3):85-9, 92-3. doi: 10.1080/00325481.1993.11945707. Postgrad Med. 1993. PMID: 8361945 Review.
Genetics of manic depressive illness.
MacKinnon DF, Jamison KR, DePaulo JR. MacKinnon DF, et al. Among authors: depaulo jr. Annu Rev Neurosci. 1997;20:355-73. doi: 10.1146/annurev.neuro.20.1.355. Annu Rev Neurosci. 1997. PMID: 9056718 Review.
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q.
Detera-Wadleigh SD, Badner JA, Yoshikawa T, Sanders AR, Goldin LR, Turner G, Rollins DY, Moses T, Guroff JJ, Kazuba D, Maxwell ME, Edenberg HJ, Foroud T, Lahiri D, Nurnberger JI Jr, Stine OC, McMahon F, Meyers DA, MacKinnon D, Simpson S, McInnis M, DePaulo JR, Rice J, Goate A, Gershon ES, et al. Detera-Wadleigh SD, et al. Among authors: depaulo jr. Am J Med Genet. 1997 May 31;74(3):254-62. doi: 10.1002/(sici)1096-8628(19970531)74:3<254::aid-ajmg4>3.0.co;2-q. Am J Med Genet. 1997. PMID: 9184307
Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X.
Stine OC, McMahon FJ, Chen L, Xu J, Meyers DA, MacKinnon DF, Simpson S, McInnis MG, Rice JP, Goate A, Reich T, Edenberg HJ, Foroud T, Nurnberger JI Jr, Detera-Wadleigh SD, Goldin LR, Guroff J, Gershon ES, Blehar MC, DePaulo JR. Stine OC, et al. Among authors: depaulo jr. Am J Med Genet. 1997 May 31;74(3):263-9. Am J Med Genet. 1997. PMID: 9184308
Panic disorder with familial bipolar disorder.
MacKinnon DF, McMahon FJ, Simpson SG, McInnis MG, DePaulo JR. MacKinnon DF, et al. Among authors: depaulo jr. Biol Psychiatry. 1997 Jul 15;42(2):90-5. doi: 10.1016/S0006-3223(96)00299-5. Biol Psychiatry. 1997. PMID: 9209725 Free article.
Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype.
Friddle C, Koskela R, Ranade K, Hebert J, Cargill M, Clark CD, McInnis M, Simpson S, McMahon F, Stine OC, Meyers D, Xu J, MacKinnon D, Swift-Scanlan T, Jamison K, Folstein S, Daly M, Kruglyak L, Marr T, DePaulo JR, Botstein D. Friddle C, et al. Among authors: depaulo jr. Am J Hum Genet. 2000 Jan;66(1):205-15. doi: 10.1086/302697. Am J Hum Genet. 2000. PMID: 10631152 Free PMC article.
Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees.
Foroud T, Castelluccio PF, Koller DL, Edenberg HJ, Miller M, Bowman E, Rau NL, Smiley C, Rice JP, Goate A, Armstrong C, Bierut LJ, Reich T, Detera-Wadleigh SD, Goldin LR, Badner JA, Guroff JJ, Gershon ES, McMahon FJ, Simpson S, MacKinnon D, McInnis M, Stine OC, DePaulo JR, Blehar MC, Nurnberger JI Jr. Foroud T, et al. Among authors: depaulo jr. Am J Med Genet. 2000 Feb 7;96(1):18-23. Am J Med Genet. 2000. PMID: 10686547
205 results