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New insights in the targets of action of dimethyl fumarate in endothelial cells: effects on energetic metabolism and serine synthesis in vitro and in vivo.
Ocaña MC, Bernal M, Yang C, Caro C, Domínguez A, Vu HS, Cárdenas C, García-Martín ML, DeBerardinis RJ, Quesada AR, Martínez-Poveda B, Medina MÁ. Ocaña MC, et al. Among authors: deberardinis rj. Commun Biol. 2023 Oct 25;6(1):1084. doi: 10.1038/s42003-023-05443-4. Commun Biol. 2023. PMID: 37880317 Free PMC article.
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Cheng T, Sudderth J, Yang C, Mullen AR, Jin ES, Matés JM, DeBerardinis RJ. Cheng T, et al. Among authors: deberardinis rj. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8674-9. doi: 10.1073/pnas.1016627108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555572 Free PMC article.
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
Marin-Valencia I, Yang C, Mashimo T, Cho S, Baek H, Yang XL, Rajagopalan KN, Maddie M, Vemireddy V, Zhao Z, Cai L, Good L, Tu BP, Hatanpaa KJ, Mickey BE, Matés JM, Pascual JM, Maher EA, Malloy CR, Deberardinis RJ, Bachoo RM. Marin-Valencia I, et al. Among authors: deberardinis rj. Cell Metab. 2012 Jun 6;15(6):827-37. doi: 10.1016/j.cmet.2012.05.001. Cell Metab. 2012. PMID: 22682223 Free PMC article.
Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans.
Ni M, Solmonson A, Pan C, Yang C, Li D, Notzon A, Cai L, Guevara G, Zacharias LG, Faubert B, Vu HS, Jiang L, Ko B, Morales NM, Pei J, Vale G, Rakheja D, Grishin NV, McDonald JG, Gotway GK, McNutt MC, Pascual JM, DeBerardinis RJ. Ni M, et al. Among authors: deberardinis rj. Cell Rep. 2019 Apr 30;27(5):1376-1386.e6. doi: 10.1016/j.celrep.2019.04.005. Cell Rep. 2019. PMID: 31042466 Free PMC article.
Using arterial-venous analysis to characterize cancer metabolic consumption in patients.
Xiong N, Gao X, Zhao H, Cai F, Zhang FC, Yuan Y, Liu W, He F, Zacharias LG, Lin H, Vu HS, Xing C, Yao DX, Chen F, Luo B, Sun W, DeBerardinis RJ, Xu H, Ge WP. Xiong N, et al. Among authors: deberardinis rj. Nat Commun. 2020 Jun 23;11(1):3169. doi: 10.1038/s41467-020-16810-8. Nat Commun. 2020. PMID: 32576825 Free PMC article.
Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer.
Cai L, Liu H, Huang F, Fujimoto J, Girard L, Chen J, Li Y, Zhang YA, Deb D, Stastny V, Pozo K, Kuo CS, Jia G, Yang C, Zou W, Alomar A, Huffman K, Papari-Zareei M, Yang L, Drapkin B, Akbay EA, Shames DS, Wistuba II, Wang T, Johnson JE, Xiao G, DeBerardinis RJ, Minna JD, Xie Y, Gazdar AF. Cai L, et al. Among authors: deberardinis rj. Commun Biol. 2021 Mar 9;4(1):314. doi: 10.1038/s42003-021-01842-7. Commun Biol. 2021. PMID: 33750914 Free PMC article.
Mitochondrial NADP+ is essential for proline biosynthesis during cell growth.
Tran DH, Kesavan R, Rion H, Soflaee MH, Solmonson A, Bezwada D, Vu HS, Cai F, Phillips JA 3rd, DeBerardinis RJ, Hoxhaj G. Tran DH, et al. Among authors: deberardinis rj. Nat Metab. 2021 Apr;3(4):571-585. doi: 10.1038/s42255-021-00374-y. Epub 2021 Apr 8. Nat Metab. 2021. PMID: 33833463 Free PMC article.
272 results