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MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
Qian Y, Galan-Cobo A, Guijarro I, Dang M, Molkentine D, Poteete A, Zhang F, Wang Q, Wang J, Parra E, Panda A, Fang J, Skoulidis F, Wistuba II, Verma S, Merghoub T, Wolchok JD, Wong KK, DeBerardinis RJ, Minna JD, Vokes NI, Meador CB, Gainor JF, Wang L, Reuben A, Heymach JV. Qian Y, et al. Among authors: deberardinis rj. Cancer Cell. 2023 Jul 10;41(7):1363-1380.e7. doi: 10.1016/j.ccell.2023.05.015. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327788
Novel pathogenic UQCRC2 variants in a female with normal neurodevelopment.
Abou Haidar L, Harris RC, Pachnis P, Chen H, Gotway GK, Ni M, DeBerardinis RJ. Abou Haidar L, et al. Among authors: deberardinis rj. Cold Spring Harb Mol Case Stud. 2024 Jan 10;9(4):a006295. doi: 10.1101/mcs.a006295. Print 2023 Dec. Cold Spring Harb Mol Case Stud. 2024. PMID: 37709555 Free PMC article.
FDA approved drugs with antiviral activity against SARS-CoV-2: From structure-based repurposing to host-specific mechanisms.
Ahmed MS, Farag AB, Boys IN, Wang P, Menendez-Montes I, Nguyen NUN, Eitson JL, Ohlson MB, Fan W, McDougal MB, Mar K, Thet S, Ortiz F, Kim SY, Solmonson A, Williams NS, Lemoff A, DeBerardinis RJ, Schoggins JW, Sadek HA. Ahmed MS, et al. Among authors: deberardinis rj. Biomed Pharmacother. 2023 Jun;162:114614. doi: 10.1016/j.biopha.2023.114614. Epub 2023 Mar 28. Biomed Pharmacother. 2023. PMID: 37068330 Free PMC article.
Glutamine antagonists may KEAP lung cancer in check.
Blatt EB, DeBerardinis RJ. Blatt EB, et al. Among authors: deberardinis rj. Sci Adv. 2024 Mar 29;10(13):eado7808. doi: 10.1126/sciadv.ado7808. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536918 Free PMC article. Review.
272 results