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Theranostics in immuno-oncology using nanobody derivatives.
Lecocq Q, De Vlaeminck Y, Hanssens H, D'Huyvetter M, Raes G, Goyvaerts C, Keyaerts M, Devoogdt N, Breckpot K. Lecocq Q, et al. Among authors: de vlaeminck y. Theranostics. 2019 Oct 15;9(25):7772-7791. doi: 10.7150/thno.34941. eCollection 2019. Theranostics. 2019. PMID: 31695800 Free PMC article. Review.
Cancer-Associated Myeloid Regulatory Cells.
De Vlaeminck Y, González-Rascón A, Goyvaerts C, Breckpot K. De Vlaeminck Y, et al. Front Immunol. 2016 Mar 29;7:113. doi: 10.3389/fimmu.2016.00113. eCollection 2016. Front Immunol. 2016. PMID: 27065074 Free PMC article. Review.
Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages.
De Vlaeminck Y, Lecocq Q, Giron P, Heirman C, Geeraerts X, Bolli E, Movahedi K, Massa S, Schoonooghe S, Thielemans K, Goyvaerts C, Van Ginderachter JA, Breckpot K. De Vlaeminck Y, et al. J Control Release. 2019 Apr 10;299:107-120. doi: 10.1016/j.jconrel.2019.02.023. Epub 2019 Feb 21. J Control Release. 2019. PMID: 30797866
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade.
Lecocq Q, Awad RM, De Vlaeminck Y, de Mey W, Ertveldt T, Goyvaerts C, Raes G, Thielemans K, Keyaerts M, Devoogdt N, Breckpot K. Lecocq Q, et al. Among authors: de mey w, de vlaeminck y. J Nucl Med. 2021 Nov;62(11):1638-1644. doi: 10.2967/jnumed.120.258871. Epub 2021 Mar 12. J Nucl Med. 2021. PMID: 33712537 Free PMC article.
Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade.
Awad RM, Lecocq Q, Zeven K, Ertveldt T, De Beck L, Ceuppens H, Broos K, De Vlaeminck Y, Goyvaerts C, Verdonck M, Raes G, Van Parys A, Cauwels A, Keyaerts M, Devoogdt N, Breckpot K. Awad RM, et al. Among authors: de vlaeminck y. Mol Ther Methods Clin Dev. 2021 Jun 4;22:172-182. doi: 10.1016/j.omtm.2021.05.017. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485603 Free PMC article.
TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy.
De Ridder K, Locy H, Piccioni E, Zuazo MI, Awad RM, Verhulst S, Van Bulck M, De Vlaeminck Y, Lecocq Q, Reijmen E, De Mey W, De Beck L, Ertveldt T, Pintelon I, Timmermans JP, Escors D, Keyaerts M, Breckpot K, Goyvaerts C. De Ridder K, et al. Among authors: de vlaeminck y. Front Immunol. 2022 Apr 14;13:811867. doi: 10.3389/fimmu.2022.811867. eCollection 2022. Front Immunol. 2022. PMID: 35493461 Free PMC article.
Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177-Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model.
Ertveldt T, De Beck L, De Ridder K, Locy H, de Mey W, Goyvaerts C, Lecocq Q, Ceuppens H, De Vlaeminck Y, Awad RM, Keyaerts M, Devoogdt N, D'Huyvetter M, Breckpot K, Krasniqi A. Ertveldt T, et al. Among authors: de vlaeminck y. Mol Cancer Ther. 2022 Jul 5;21(7):1136-1148. doi: 10.1158/1535-7163.MCT-21-0791. Mol Cancer Ther. 2022. PMID: 35499391 Free PMC article.
21 results