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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Cobo-Vuilleumier N, Lorenzo PI, Rodríguez NG, Herrera Gómez IG, Fuente-Martin E, López-Noriega L, Mellado-Gil JM, Romero-Zerbo SY, Baquié M, Lachaud CC, Stifter K, Perdomo G, Bugliani M, De Tata V, Bosco D, Parnaud G, Pozo D, Hmadcha A, Florido JP, Toscano MG, de Haan P, Schoonjans K, Sánchez Palazón L, Marchetti P, Schirmbeck R, Martín-Montalvo A, Meda P, Soria B, Bermúdez-Silva FJ, St-Onge L, Gauthier BR. Cobo-Vuilleumier N, et al. Among authors: de haan p, de tata v. Nat Commun. 2018 Apr 16;9(1):1488. doi: 10.1038/s41467-018-03943-0. Nat Commun. 2018. PMID: 29662071 Free PMC article.
Mast Cells and the Pancreas in Human Type 1 and Type 2 Diabetes.
Masini M, Suleiman M, Novelli M, Marselli L, Marchetti P, De Tata V. Masini M, et al. Among authors: de tata v. Cells. 2021 Jul 23;10(8):1875. doi: 10.3390/cells10081875. Cells. 2021. PMID: 34440644 Free PMC article. Review.
Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes.
Marchetti P, Bugliani M, De Tata V, Suleiman M, Marselli L. Marchetti P, et al. Among authors: de tata v. Front Cell Dev Biol. 2017 May 23;5:55. doi: 10.3389/fcell.2017.00055. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 28589121 Free PMC article. Review.
Mast cells infiltrate pancreatic islets in human type 1 diabetes.
Martino L, Masini M, Bugliani M, Marselli L, Suleiman M, Boggi U, Nogueira TC, Filipponi F, Occhipinti M, Campani D, Dotta F, Syed F, Eizirik DL, Marchetti P, De Tata V. Martino L, et al. Among authors: de tata v. Diabetologia. 2015 Nov;58(11):2554-62. doi: 10.1007/s00125-015-3734-1. Epub 2015 Aug 15. Diabetologia. 2015. PMID: 26276263
DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes.
Bugliani M, Syed F, Paula FMM, Omar BA, Suleiman M, Mossuto S, Grano F, Cardarelli F, Boggi U, Vistoli F, Filipponi F, De Simone P, Marselli L, De Tata V, Ahren B, Eizirik DL, Marchetti P. Bugliani M, et al. Among authors: de tata v, de simone p. Mol Cell Endocrinol. 2018 Sep 15;473:186-193. doi: 10.1016/j.mce.2018.01.019. Epub 2018 Feb 1. Mol Cell Endocrinol. 2018. PMID: 29409957
77 results