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Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity.
Madia VN, Messore A, Pescatori L, Saccoliti F, Tudino V, De Leo A, Bortolami M, Scipione L, Costi R, Rivara S, Scalvini L, Mor M, Ferrara FF, Pavoni E, Roscilli G, Cassinelli G, Milazzo FM, Battistuzzi G, Di Santo R, Giannini G. Madia VN, et al. Among authors: de leo a. J Med Chem. 2018 Aug 9;61(15):6918-6936. doi: 10.1021/acs.jmedchem.8b00908. Epub 2018 Jul 30. J Med Chem. 2018. PMID: 30010344
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity.
Messore A, Madia VN, Pescatori L, Saccoliti F, Tudino V, De Leo A, Bortolami M, De Vita D, Scipione L, Pepi F, Costi R, Rivara S, Scalvini L, Mor M, Ferrara FF, Pavoni E, Roscilli G, Cassinelli G, Milazzo FM, Battistuzzi G, Di Santo R, Giannini G. Messore A, et al. Among authors: de vita d, de leo a. J Med Chem. 2018 Dec 13;61(23):10834-10859. doi: 10.1021/acs.jmedchem.8b01497. Epub 2018 Nov 29. J Med Chem. 2018. PMID: 30412404 Free article.
In Vitro Antiviral Activity of New Oxazoline Derivatives as Potent Poliovirus Inhibitors.
Madia VN, Messore A, Pescatori L, Saccoliti F, Tudino V, De Leo A, Scipione L, Fiore L, Rhoden E, Manetti F, Oberste MS, Di Santo R, Costi R. Madia VN, et al. Among authors: de leo a. J Med Chem. 2019 Jan 24;62(2):798-810. doi: 10.1021/acs.jmedchem.8b01482. Epub 2018 Dec 18. J Med Chem. 2019. PMID: 30512950 Free PMC article.
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Pepe G, Cirilli R, Faggi C, Di Marco A, Battista MR, Summa V, Costi R, Di Santo R. Saccoliti F, et al. Among authors: de vita d, de leo a. J Med Chem. 2019 Feb 14;62(3):1330-1347. doi: 10.1021/acs.jmedchem.8b01464. Epub 2019 Jan 23. J Med Chem. 2019. PMID: 30615444
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase.
Messore A, Corona A, Madia VN, Saccoliti F, Tudino V, De Leo A, Scipione L, De Vita D, Amendola G, Di Maro S, Novellino E, Cosconati S, Métifiot M, Andreola ML, Valenti P, Esposito F, Grandi N, Tramontano E, Costi R, Di Santo R. Messore A, et al. Among authors: de vita d, de leo a. ACS Med Chem Lett. 2020 Mar 5;11(5):798-805. doi: 10.1021/acsmedchemlett.9b00617. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435387 Free PMC article.
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase.
Messore A, Corona A, Madia VN, Saccoliti F, Tudino V, De Leo A, Ialongo D, Scipione L, De Vita D, Amendola G, Novellino E, Cosconati S, Métifiot M, Andreola ML, Esposito F, Grandi N, Tramontano E, Costi R, Di Santo R. Messore A, et al. Among authors: de vita d, de leo a. J Med Chem. 2021 Jun 24;64(12):8579-8598. doi: 10.1021/acs.jmedchem.1c00535. Epub 2021 Jun 9. J Med Chem. 2021. PMID: 34106711 Free PMC article.
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Costi R, Di Santo R. Saccoliti F, et al. Among authors: de vita d, de leo a. Eur J Med Chem. 2018 Aug 5;156:53-60. doi: 10.1016/j.ejmech.2018.06.063. Epub 2018 Jun 28. Eur J Med Chem. 2018. PMID: 30006174
Tegaserod for the Treatment of Irritable Bowel Syndrome.
Madia VN, Messore A, Saccoliti F, Tudino V, De Leo A, De Vita D, Bortolami M, Scipione L, Pindinello I, Costi R, Di Santo R. Madia VN, et al. Among authors: de vita d, de leo a. Antiinflamm Antiallergy Agents Med Chem. 2020;19(4):342-369. doi: 10.2174/1871523018666190911121306. Antiinflamm Antiallergy Agents Med Chem. 2020. PMID: 31518227 Free PMC article. Review.
385 results