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Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis.
Ortega-Ferreira C, Soret P, Robin G, Speca S, Hubert S, Le Gall M, Desvaux E, Jendoubi M, Saint-Paul J, Chadli L, Chomel A, Berger S, Nony E, Neau B, Fould B, Licznar A, Levasseur F, Guerrier T, Elouej S, Courtade-Gaïani S, Provost N, Nguyen TQ, Verdier J, Launay D, De Ceuninck F. Ortega-Ferreira C, et al. Among authors: de ceuninck f. Nat Commun. 2023 Aug 31;14(1):5291. doi: 10.1038/s41467-023-41117-9. Nat Commun. 2023. PMID: 37652913 Free PMC article.
S95021, a novel selective and pan-neutralizing anti interferon alpha (IFN-α) monoclonal antibody as a candidate treatment for selected autoimmune rheumatic diseases.
Duguet F, Ortega-Ferreira C, Fould B, Darville H, Berger S, Chomel A, Leclerc G, Kisand K, Haljasmägi L, Hayday AC, Desvaux E, Nony E, Moingeon P, De Ceuninck F. Duguet F, et al. Among authors: de ceuninck f. J Transl Autoimmun. 2021 Mar 1;4:100093. doi: 10.1016/j.jtauto.2021.100093. eCollection 2021. J Transl Autoimmun. 2021. PMID: 33748735 Free PMC article.
Applications of transcriptomics in support of drug development for osteoarthritis.
Kaplon H, Luo Y, De Ceuninck F, Lalande A, Courtade-Gaiani S, Laigle L, Moingeon P. Kaplon H, et al. Among authors: de ceuninck f. Osteoarthr Cartil Open. 2021 Nov 18;3(4):100221. doi: 10.1016/j.ocarto.2021.100221. eCollection 2021 Dec. Osteoarthr Cartil Open. 2021. PMID: 36474760 Free PMC article.
Targeting galectin-3 in inflammatory and fibrotic diseases.
Bouffette S, Botez I, De Ceuninck F. Bouffette S, et al. Among authors: de ceuninck f. Trends Pharmacol Sci. 2023 Aug;44(8):519-531. doi: 10.1016/j.tips.2023.06.001. Epub 2023 Jun 28. Trends Pharmacol Sci. 2023. PMID: 37391294 Free article. Review.
Access to Galectin-3 Inhibitors from Chemoenzymatic Synthons.
Dussouy C, Téletchéa S, Lambert A, Charlier C, Botez I, De Ceuninck F, Grandjean C. Dussouy C, et al. Among authors: de ceuninck f. J Org Chem. 2020 Dec 18;85(24):16099-16114. doi: 10.1021/acs.joc.0c01927. Epub 2020 Nov 17. J Org Chem. 2020. PMID: 33200927
Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans.
De Ceuninck F, Kargar C, Ilic C, Caliez A, Rolin JO, Umbdenstock T, Vinson C, Combettes M, de Fanti B, Harley E, Sadlo M, Lefèvre AL, Broux O, Wierzbicki M, Fourquez JM, Perron-Sierra F, Kotschy A, Ktorza A. De Ceuninck F, et al. Among authors: de fanti b. Br J Pharmacol. 2013 Jan;168(2):339-53. doi: 10.1111/j.1476-5381.2012.02184.x. Br J Pharmacol. 2013. PMID: 22925001 Free PMC article.
43 results