Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.
Sparkes A, De Baetselier P, Brys L, Cabrito I, Sterckx YG, Schoonooghe S, Muyldermans S, Raes G, Bucala R, Vanlandschoot P, Van Ginderachter JA, Stijlemans B.
Sparkes A, et al. Among authors: de baetselier p.
FASEB J. 2018 Jun;32(6):3411-3422. doi: 10.1096/fj.201701189R. Epub 2018 Jan 25.
FASEB J. 2018.
PMID: 29401625
Free PMC article.
Hence, Nbs, with their structural and pharmacologic advantages over currently available inhibitors, may be an effective, novel approach to interfere with the action of MIF in septic shock and other conditions of inflammatory end-organ damage.-Sparkes, A., De Baetselier …
Hence, Nbs, with their structural and pharmacologic advantages over currently available inhibitors, may be an effective, novel approach to i …