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Page 1
Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas.
De Bacco F, Orzan F, Crisafulli G, Prelli M, Isella C, Casanova E, Albano R, Reato G, Erriquez J, D'Ambrosio A, Panero M, Dall'Aglio C, Casorzo L, Cominelli M, Pagani F, Melcarne A, Zeppa P, Altieri R, Morra I, Cassoni P, Garbossa D, Cassisa A, Bartolini A, Pellegatta S, Comoglio PM, Finocchiaro G, Poliani PL, Boccaccio C. De Bacco F, et al. Cell Rep. 2023 Aug 29;42(8):112816. doi: 10.1016/j.celrep.2023.112816. Epub 2023 Jul 27. Cell Rep. 2023. PMID: 37505981 Free article.
The MET oncogene is a functional marker of a glioblastoma stem cell subtype.
De Bacco F, Casanova E, Medico E, Pellegatta S, Orzan F, Albano R, Luraghi P, Reato G, D'Ambrosio A, Porrati P, Patanè M, Maderna E, Pollo B, Comoglio PM, Finocchiaro G, Boccaccio C. De Bacco F, et al. Cancer Res. 2012 Sep 1;72(17):4537-50. doi: 10.1158/0008-5472.CAN-11-3490. Epub 2012 Jun 26. Cancer Res. 2012. PMID: 22738909 Free article.
MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors.
Luraghi P, Reato G, Cipriano E, Sassi F, Orzan F, Bigatto V, De Bacco F, Menietti E, Han M, Rideout WM 3rd, Perera T, Bertotti A, Trusolino L, Comoglio PM, Boccaccio C. Luraghi P, et al. Among authors: de bacco f. Cancer Res. 2014 Mar 15;74(6):1857-69. doi: 10.1158/0008-5472.CAN-13-2340-T. Epub 2014 Jan 21. Cancer Res. 2014. PMID: 24448239 Free article.
TNF-α promotes invasive growth through the MET signaling pathway.
Bigatto V, De Bacco F, Casanova E, Reato G, Lanzetti L, Isella C, Sarotto I, Comoglio PM, Boccaccio C. Bigatto V, et al. Among authors: de bacco f. Mol Oncol. 2015 Feb;9(2):377-88. doi: 10.1016/j.molonc.2014.09.002. Epub 2014 Sep 26. Mol Oncol. 2015. PMID: 25306394 Free PMC article.
MET inhibition overcomes radiation resistance of glioblastoma stem-like cells.
De Bacco F, D'Ambrosio A, Casanova E, Orzan F, Neggia R, Albano R, Verginelli F, Cominelli M, Poliani PL, Luraghi P, Reato G, Pellegatta S, Finocchiaro G, Perera T, Garibaldi E, Gabriele P, Comoglio PM, Boccaccio C. De Bacco F, et al. EMBO Mol Med. 2016 May 2;8(5):550-68. doi: 10.15252/emmm.201505890. Print 2016 May. EMBO Mol Med. 2016. PMID: 27138567 Free PMC article.
Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor.
Orzan F, De Bacco F, Crisafulli G, Pellegatta S, Mussolin B, Siravegna G, D'Ambrosio A, Comoglio PM, Finocchiaro G, Boccaccio C. Orzan F, et al. Among authors: de bacco f. Stem Cells. 2017 Nov;35(11):2218-2228. doi: 10.1002/stem.2703. Epub 2017 Sep 29. Stem Cells. 2017. PMID: 28895245 Free article.
A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy.
Luraghi P, Bigatto V, Cipriano E, Reato G, Orzan F, Sassi F, De Bacco F, Isella C, Bellomo SE, Medico E, Comoglio PM, Bertotti A, Trusolino L, Boccaccio C. Luraghi P, et al. Among authors: de bacco f. Clin Cancer Res. 2018 Feb 15;24(4):807-820. doi: 10.1158/1078-0432.CCR-17-2151. Epub 2017 Oct 3. Clin Cancer Res. 2018. PMID: 28974546 Free article.
A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes.
Orzan F, Pagani F, Cominelli M, Triggiani L, Calza S, De Bacco F, Medicina D, Balzarini P, Panciani PP, Liserre R, Buglione M, Fontanella MM, Medico E, Galli R, Isella C, Boccaccio C, Poliani PL; on behalf of the Neuro-Oncology group of Spedali Civili of Brescia. Orzan F, et al. Among authors: de bacco f. Lab Invest. 2020 Oct;100(10):1330-1344. doi: 10.1038/s41374-020-0437-0. Epub 2020 May 13. Lab Invest. 2020. PMID: 32404931 Free article.
ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma.
De Bacco F, Orzan F, Erriquez J, Casanova E, Barault L, Albano R, D'Ambrosio A, Bigatto V, Reato G, Patanè M, Pollo B, Kuesters G, Dell'Aglio C, Casorzo L, Pellegatta S, Finocchiaro G, Comoglio PM, Boccaccio C. De Bacco F, et al. Cell Rep. 2021 Jul 27;36(4):109455. doi: 10.1016/j.celrep.2021.109455. Cell Rep. 2021. PMID: 34320350 Free article.
17 results