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Improving the Gastrointestinal Stability of Linaclotide.
Braga Emidio N, Tran HNT, Andersson A, Dawson PE, Albericio F, Vetter I, Muttenthaler M. Braga Emidio N, et al. Among authors: dawson pe. J Med Chem. 2021 Jun 24;64(12):8384-8390. doi: 10.1021/acs.jmedchem.1c00380. Epub 2021 May 12. J Med Chem. 2021. PMID: 33979161 Free PMC article.
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW. Koehbach J, et al. Among authors: dawson pe. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248349 Free PMC article.
Two for the Price of One: Heterobivalent Ligand Design Targeting Two Binding Sites on Voltage-Gated Sodium Channels Slows Ligand Dissociation and Enhances Potency.
Peschel A, Cardoso FC, Walker AA, Durek T, Stone MRL, Braga Emidio N, Dawson PE, Muttenthaler M, King GF. Peschel A, et al. Among authors: dawson pe. J Med Chem. 2020 Nov 12;63(21):12773-12785. doi: 10.1021/acs.jmedchem.0c01107. Epub 2020 Oct 20. J Med Chem. 2020. PMID: 33078946 Free PMC article.
Expedient on-resin synthesis of peptidic benzimidazoles.
Bird MJ, Silvestri AP, Dawson PE. Bird MJ, et al. Among authors: dawson pe. Bioorg Med Chem Lett. 2018 Sep 1;28(16):2679-2681. doi: 10.1016/j.bmcl.2018.04.062. Epub 2018 May 3. Bioorg Med Chem Lett. 2018. PMID: 29739642 Free PMC article.
Modern Peptide and Protein Chemistry: Reaching New Heights.
Hackenberger CPR, Dawson PE, Chen YX, Hojo H. Hackenberger CPR, et al. Among authors: dawson pe. J Org Chem. 2020 Feb 7;85(3):1328-1330. doi: 10.1021/acs.joc.0c00104. J Org Chem. 2020. PMID: 32028772 No abstract available.
217 results