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Design of Next Generation Polymyxins with Lower Toxicity: The Discovery of SPR206.
Brown P, Abbott E, Abdulle O, Boakes S, Coleman S, Divall N, Duperchy E, Moss S, Rivers D, Simonovic M, Singh J, Stanway S, Wilson A, Dawson MJ. Brown P, et al. Among authors: dawson mj. ACS Infect Dis. 2019 Oct 11;5(10):1645-1656. doi: 10.1021/acsinfecdis.9b00217. Epub 2019 Sep 24. ACS Infect Dis. 2019. PMID: 31525992 Free PMC article.
Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin.
Brown P, Abdulle O, Boakes S, Divall N, Duperchy E, Ganeshwaran S, Lester R, Moss S, Rivers D, Simonovic M, Singh J, Stanway S, Wilson A, Dawson MJ. Brown P, et al. Among authors: dawson mj. ACS Infect Dis. 2021 Apr 9;7(4):894-905. doi: 10.1021/acsinfecdis.0c00917. Epub 2021 Mar 10. ACS Infect Dis. 2021. PMID: 33688718 Free PMC article.
Alternatives to antibiotics-a pipeline portfolio review.
Czaplewski L, Bax R, Clokie M, Dawson M, Fairhead H, Fischetti VA, Foster S, Gilmore BF, Hancock RE, Harper D, Henderson IR, Hilpert K, Jones BV, Kadioglu A, Knowles D, Ólafsdóttir S, Payne D, Projan S, Shaunak S, Silverman J, Thomas CM, Trust TJ, Warn P, Rex JH. Czaplewski L, et al. Lancet Infect Dis. 2016 Feb;16(2):239-51. doi: 10.1016/S1473-3099(15)00466-1. Epub 2016 Jan 13. Lancet Infect Dis. 2016. PMID: 26795692 Free article. Review.
Dissecting structural and functional diversity of the lantibiotic mersacidin.
Appleyard AN, Choi S, Read DM, Lightfoot A, Boakes S, Hoffmann A, Chopra I, Bierbaum G, Rudd BA, Dawson MJ, Cortes J. Appleyard AN, et al. Among authors: dawson mj. Chem Biol. 2009 May 29;16(5):490-8. doi: 10.1016/j.chembiol.2009.03.011. Chem Biol. 2009. PMID: 19477413 Free PMC article.
106 results