Davtyan H - Search Results

1

Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure.

Chen X, Sun G, Tian E, Zhang M, Davtyan H, Beach TG, Reiman EM, Blurton-Jones M, Holtzman DM, Shi Y. Chen X, et al. Among authors: davtyan h. Adv Sci (Weinh). 2021 Sep;8(18):e2101462. doi: 10.1002/advs.202101462. Epub 2021 Aug 2. Adv Sci (Weinh). 2021. PMID: 34337898 Free PMC article.

2

The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.

Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW, Blurton-Jones M. Marsh SE, et al. Among authors: davtyan h. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1316-25. doi: 10.1073/pnas.1525466113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884167 Free PMC article.

3

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies.

Goldberg NRS, Marsh SE, Ochaba J, Shelley BC, Davtyan H, Thompson LM, Steffan JS, Svendsen CN, Blurton-Jones M. Goldberg NRS, et al. Among authors: davtyan h. Stem Cells Transl Med. 2017 Jun;6(6):1477-1490. doi: 10.1002/sctm.16-0362. Epub 2017 Feb 22. Stem Cells Transl Med. 2017. PMID: 28225193 Free PMC article.

4

MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.

Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Kazarian K, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Davtyan H, et al. Vaccine. 2017 Apr 11;35(16):2015-2024. doi: 10.1016/j.vaccine.2017.03.020. Epub 2017 Mar 18. Vaccine. 2017. PMID: 28320590 Free PMC article.

5

Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency.

Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, Cribbs DH, Ghochikyan A. Agadjanyan MG, et al. Among authors: davtyan h. Mol Neurodegener. 2017 May 5;12(1):33. doi: 10.1186/s13024-017-0172-1. Mol Neurodegener. 2017. PMID: 28472993 Free PMC article.

6

MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency.

Davtyan H, Zagorski K, Petrushina I, Kazarian K, Goldberg NRS, Petrosyan J, Blurton-Jones M, Masliah E, Cribbs DH, Agadjanyan MG, Ghochikyan A. Davtyan H, et al. Neurobiol Aging. 2017 Nov;59:156-170. doi: 10.1016/j.neurobiolaging.2017.08.006. Epub 2017 Aug 10. Neurobiol Aging. 2017. PMID: 28870518 Free PMC article.

7

Development and validation of a simplified method to generate human microglia from pluripotent stem cells.

McQuade A, Coburn M, Tu CH, Hasselmann J, Davtyan H, Blurton-Jones M. McQuade A, et al. Among authors: davtyan h. Mol Neurodegener. 2018 Dec 22;13(1):67. doi: 10.1186/s13024-018-0297-x. Mol Neurodegener. 2018. PMID: 30577865 Free PMC article.

8

Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions.

Faal T, Phan DTT, Davtyan H, Scarfone VM, Varady E, Blurton-Jones M, Hughes CCW, Inlay MA. Faal T, et al. Among authors: davtyan h. Stem Cell Reports. 2019 Mar 5;12(3):451-460. doi: 10.1016/j.stemcr.2019.01.005. Epub 2019 Feb 7. Stem Cell Reports. 2019. PMID: 30745035 Free PMC article.

9

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations.

Rojo R, Raper A, Ozdemir DD, Lefevre L, Grabert K, Wollscheid-Lengeling E, Bradford B, Caruso M, Gazova I, Sánchez A, Lisowski ZM, Alves J, Molina-Gonzalez I, Davtyan H, Lodge RJ, Glover JD, Wallace R, Munro DAD, David E, Amit I, Miron VE, Priller J, Jenkins SJ, Hardingham GE, Blurton-Jones M, Mabbott NA, Summers KM, Hohenstein P, Hume DA, Pridans C. Rojo R, et al. Among authors: davtyan h. Nat Commun. 2019 Jul 19;10(1):3215. doi: 10.1038/s41467-019-11053-8. Nat Commun. 2019. PMID: 31324781 Free PMC article.

10

Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo.

Hasselmann J, Coburn MA, England W, Figueroa Velez DX, Kiani Shabestari S, Tu CH, McQuade A, Kolahdouzan M, Echeverria K, Claes C, Nakayama T, Azevedo R, Coufal NG, Han CZ, Cummings BJ, Davtyan H, Glass CK, Healy LM, Gandhi SP, Spitale RC, Blurton-Jones M. Hasselmann J, et al. Among authors: davtyan h. Neuron. 2019 Sep 25;103(6):1016-1033.e10. doi: 10.1016/j.neuron.2019.07.002. Epub 2019 Jul 30. Neuron. 2019. PMID: 31375314 Free PMC article.

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