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Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.
Schwartz DM, Farley TK, Richoz N, Yao C, Shih HY, Petermann F, Zhang Y, Sun HW, Hayes E, Mikami Y, Jiang K, Davis FP, Kanno Y, Milner JD, Siegel R, Laurence A, Meylan F, O'Shea JJ. Schwartz DM, et al. Among authors: davis fp. Immunity. 2019 Jan 15;50(1):106-120.e10. doi: 10.1016/j.immuni.2018.12.014. Immunity. 2019. PMID: 30650370 Free PMC article.
A Metabolic Switch for Th17 Pathogenicity.
Davis FP, Kanno Y, O'Shea JJ. Davis FP, et al. Cell. 2015 Dec 3;163(6):1308-10. doi: 10.1016/j.cell.2015.11.033. Cell. 2015. PMID: 26638065 Free article.
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.
Afzali B, Grönholm J, Vandrovcova J, O'Brien C, Sun HW, Vanderleyden I, Davis FP, Khoder A, Zhang Y, Hegazy AN, Villarino AV, Palmer IW, Kaufman J, Watts NR, Kazemian M, Kamenyeva O, Keith J, Sayed A, Kasperaviciute D, Mueller M, Hughes JD, Fuss IJ, Sadiyah MF, Montgomery-Recht K, McElwee J, Restifo NP, Strober W, Linterman MA, Wingfield PT, Uhlig HH, Roychoudhuri R, Aitman TJ, Kelleher P, Lenardo MJ, O'Shea JJ, Cooper N, Laurence ADJ. Afzali B, et al. Among authors: davis fp. Nat Immunol. 2017 Jul;18(7):813-823. doi: 10.1038/ni.3753. Epub 2017 May 22. Nat Immunol. 2017. PMID: 28530713 Free PMC article.
Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells.
Sciumè G, Mikami Y, Jankovic D, Nagashima H, Villarino AV, Morrison T, Yao C, Signorella S, Sun HW, Brooks SR, Fang D, Sartorelli V, Nakayamada S, Hirahara K, Zitti B, Davis FP, Kanno Y, O'Shea JJ, Shih HY. Sciumè G, et al. Among authors: davis fp. Immunity. 2020 Oct 13;53(4):745-758.e4. doi: 10.1016/j.immuni.2020.09.008. Epub 2020 Oct 2. Immunity. 2020. PMID: 33010223 Free PMC article.
MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.
Mikami Y, Philips RL, Sciumè G, Petermann F, Meylan F, Nagashima H, Yao C, Davis FP, Brooks SR, Sun HW, Takahashi H, Poholek AC, Shih HY, Afzali B, Muljo SA, Hafner M, Kanno Y, O'Shea JJ. Mikami Y, et al. Among authors: davis fp. Immunity. 2021 Mar 9;54(3):514-525.e6. doi: 10.1016/j.immuni.2021.02.015. Epub 2021 Mar 2. Immunity. 2021. PMID: 33657395 Free PMC article.
A central role for STAT5 in the transcriptional programing of T helper cell metabolism.
Villarino AV, Laurence AD, Davis FP, Nivelo L, Brooks SR, Sun HW, Jiang K, Afzali B, Frasca D, Hennighausen L, Kanno Y, O'Shea JJ. Villarino AV, et al. Among authors: davis fp. Sci Immunol. 2022 Nov 25;7(77):eabl9467. doi: 10.1126/sciimmunol.abl9467. Epub 2022 Nov 25. Sci Immunol. 2022. PMID: 36427325 Free PMC article.
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