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Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma.
Jain MD, Zhao H, Wang X, Atkins R, Menges M, Reid K, Spitler K, Faramand R, Bachmeier C, Dean EA, Cao B, Chavez JC, Shah B, Lazaryan A, Nishihori T, Hussaini M, Gonzalez RJ, Mullinax JE, Rodriguez PC, Conejo-Garcia JR, Anasetti C, Davila ML, Locke FL. Jain MD, et al. Among authors: davila ml. Blood. 2021 May 13;137(19):2621-2633. doi: 10.1182/blood.2020007445. Blood. 2021. PMID: 33512407 Free PMC article.
IL-2 promotes early Treg reconstitution after allogeneic hematopoietic cell transplantation.
Betts BC, Pidala J, Kim J, Mishra A, Nishihori T, Perez L, Ochoa-Bayona JL, Khimani F, Walton K, Bookout R, Nieder M, Khaira DK, Davila M, Alsina M, Field T, Ayala E, Locke FL, Riches M, Kharfan-Dabaja M, Fernandez H, Anasetti C. Betts BC, et al. Haematologica. 2017 May;102(5):948-957. doi: 10.3324/haematol.2016.153072. Epub 2017 Jan 19. Haematologica. 2017. PMID: 28104702 Free PMC article. Clinical Trial.
In vivo IL-12/IL-23p40 neutralization blocks Th1/Th17 response after allogeneic hematopoietic cell transplantation.
Pidala J, Beato F, Kim J, Betts B, Jim H, Sagatys E, Levine JE, Ferrara JLM, Ozbek U, Ayala E, Davila M, Fernandez HF, Field T, Kharfan-Dabaja MA, Khaira D, Khimani F, Locke FL, Mishra A, Nieder M, Nishihori T, Perez L, Riches M, Anasetti C. Pidala J, et al. Haematologica. 2018 Mar;103(3):531-539. doi: 10.3324/haematol.2017.171199. Epub 2017 Dec 14. Haematologica. 2018. PMID: 29242294 Free PMC article. Clinical Trial.
CAR T cells find strength in polyfunction.
Davila ML. Davila ML. Blood. 2018 Aug 23;132(8):769-770. doi: 10.1182/blood-2018-06-858712. Blood. 2018. PMID: 30139827 Free PMC article. No abstract available.
105 results