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Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
March-Diaz R, Lara-Ureña N, Romero-Molina C, Heras-Garvin A, Ortega-de San Luis C, Alvarez-Vergara MI, Sanchez-Garcia MA, Sanchez-Mejias E, Davila JC, Rosales-Nieves AE, Forja C, Navarro V, Gomez-Arboledas A, Sanchez-Mico MV, Viehweger A, Gerpe A, Hodson EJ, Vizuete M, Bishop T, Serrano-Pozo A, Lopez-Barneo J, Berra E, Gutierrez A, Vitorica J, Pascual A. March-Diaz R, et al. Among authors: davila jc. Nat Aging. 2021 Apr;1(4):385-399. doi: 10.1038/s43587-021-00054-2. Epub 2021 Apr 15. Nat Aging. 2021. PMID: 37117599
Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative.
Navarro V, Sanchez-Mejias E, Jimenez S, Muñoz-Castro C, Sanchez-Varo R, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Navarro V, et al. Among authors: davila jc. Front Aging Neurosci. 2018 May 11;10:140. doi: 10.3389/fnagi.2018.00140. eCollection 2018. Front Aging Neurosci. 2018. PMID: 29867449 Free PMC article.
In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer's disease pathology.
Trujillo-Estrada L, Jimenez S, De Castro V, Torres M, Baglietto-Vargas D, Moreno-Gonzalez I, Navarro V, Sanchez-Varo R, Sanchez-Mejias E, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Trujillo-Estrada L, et al. Among authors: davila jc. Acta Neuropathol Commun. 2013 Nov 12;1:73. doi: 10.1186/2051-5960-1-73. Acta Neuropathol Commun. 2013. PMID: 24252759 Free PMC article.
Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration.
Sanchez-Mejias E, Navarro V, Jimenez S, Sanchez-Mico M, Sanchez-Varo R, Nuñez-Diaz C, Trujillo-Estrada L, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Sanchez-Mejias E, et al. Among authors: davila jc. Acta Neuropathol. 2016 Dec;132(6):897-916. doi: 10.1007/s00401-016-1630-5. Epub 2016 Oct 14. Acta Neuropathol. 2016. PMID: 27743026 Free PMC article.
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer's disease.
Baglietto-Vargas D, Sánchez-Mejias E, Navarro V, Jimenez S, Trujillo-Estrada L, Gómez-Arboledas A, Sánchez-Mico M, Sánchez-Varo R, Vizuete M, Dávila JC, García-Verdugo JM, Vitorica J, Gutierrez A. Baglietto-Vargas D, et al. Among authors: davila jc. Sci Rep. 2017 Aug 30;7(1):10085. doi: 10.1038/s41598-017-10353-7. Sci Rep. 2017. PMID: 28855626 Free PMC article.
Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.
Gomez-Arboledas A, Davila JC, Sanchez-Mejias E, Navarro V, Nuñez-Diaz C, Sanchez-Varo R, Sanchez-Mico MV, Trujillo-Estrada L, Fernandez-Valenzuela JJ, Vizuete M, Comella JX, Galea E, Vitorica J, Gutierrez A. Gomez-Arboledas A, et al. Among authors: davila jc. Glia. 2018 Mar;66(3):637-653. doi: 10.1002/glia.23270. Epub 2017 Nov 27. Glia. 2018. PMID: 29178139 Free PMC article.
Amyloid-β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease.
Sanchez-Mico MV, Jimenez S, Gomez-Arboledas A, Muñoz-Castro C, Romero-Molina C, Navarro V, Sanchez-Mejias E, Nuñez-Diaz C, Sanchez-Varo R, Galea E, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Sanchez-Mico MV, et al. Among authors: davila jc. Glia. 2021 Apr;69(4):997-1011. doi: 10.1002/glia.23943. Epub 2020 Dec 7. Glia. 2021. PMID: 33283891 Free article.
Non-productive angiogenesis disassembles Aß plaque-associated blood vessels.
Alvarez-Vergara MI, Rosales-Nieves AE, March-Diaz R, Rodriguez-Perinan G, Lara-Ureña N, Ortega-de San Luis C, Sanchez-Garcia MA, Martin-Bornez M, Gómez-Gálvez P, Vicente-Munuera P, Fernandez-Gomez B, Marchena MA, Bullones-Bolanos AS, Davila JC, Gonzalez-Martinez R, Trillo-Contreras JL, Sanchez-Hidalgo AC, Del Toro R, Scholl FG, Herrera E, Trepel M, Körbelin J, Escudero LM, Villadiego J, Echevarria M, de Castro F, Gutierrez A, Rabano A, Vitorica J, Pascual A. Alvarez-Vergara MI, et al. Among authors: davila jc. Nat Commun. 2021 May 25;12(1):3098. doi: 10.1038/s41467-021-23337-z. Nat Commun. 2021. PMID: 34035282 Free PMC article.
191 results