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DC isoketal-modified proteins activate T cells and promote hypertension.
Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, Shen XZ, Shyr Y, Chen SC, Mernaugh RL, Laffer CL, Elijovich F, Davies SS, Moreno H, Madhur MS, Roberts J 2nd, Harrison DG. Kirabo A, et al. Among authors: davies ss. J Clin Invest. 2014 Oct;124(10):4642-56. doi: 10.1172/JCI74084. Epub 2014 Sep 17. J Clin Invest. 2014. PMID: 25244096 Free PMC article.
Localization of isoketal adducts in vivo using a single-chain antibody.
Davies SS, Talati M, Wang X, Mernaugh RL, Amarnath V, Fessel J, Meyrick BO, Sheller J, Roberts LJ 2nd. Davies SS, et al. Free Radic Biol Med. 2004 May 1;36(9):1163-74. doi: 10.1016/j.freeradbiomed.2004.02.014. Free Radic Biol Med. 2004. PMID: 15082070
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells.
Sullivan CB, Matafonova E, Roberts LJ 2nd, Amarnath V, Davies SS. Sullivan CB, et al. Among authors: davies ss. J Lipid Res. 2010 May;51(5):999-1009. doi: 10.1194/jlr.M001040. Epub 2009 Nov 25. J Lipid Res. 2010. PMID: 19965577 Free PMC article.
Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.
Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ 2nd, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT. Sidorova TN, et al. Among authors: davies ss. J Mol Cell Cardiol. 2015 Feb;79:295-302. doi: 10.1016/j.yjmcc.2014.11.013. Epub 2014 Nov 18. J Mol Cell Cardiol. 2015. PMID: 25463275 Free PMC article.
105 results