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HDL mimetic CER-001 targets atherosclerotic plaques in patients.
Zheng KH, van der Valk FM, Smits LP, Sandberg M, Dasseux JL, Baron R, Barbaras R, Keyserling C, Coolen BF, Nederveen AJ, Verberne HJ, Nell TE, Vugts DJ, Duivenvoorden R, Fayad ZA, Mulder WJM, van Dongen GAMS, Stroes ESG. Zheng KH, et al. Among authors: dasseux jl. Atherosclerosis. 2016 Aug;251:381-388. doi: 10.1016/j.atherosclerosis.2016.05.038. Epub 2016 May 27. Atherosclerosis. 2016. PMID: 27263077 Free article.
Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA.
Kootte RS, Smits LP, van der Valk FM, Dasseux JL, Keyserling CH, Barbaras R, Paolini JF, Santos RD, van Dijk TH, Dallinga-van Thie GM, Nederveen AJ, Mulder WM, Hovingh GK, Kastelein JP, Groen AK, Stroes E. Kootte RS, et al. Among authors: dasseux jl. J Lipid Res. 2015 Mar;56(3):703-712. doi: 10.1194/jlr.M055665. Epub 2015 Jan 5. J Lipid Res. 2015. PMID: 25561459 Free PMC article. Clinical Trial.
No benefit of HDL mimetic CER-001 on carotid atherosclerosis in patients with genetically determined very low HDL levels.
Zheng KH, Kaiser Y, van Olden CC, Santos RD, Dasseux JL, Genest J, Gaudet D, Westerink J, Keyserling C, Verberne HJ, Leitersdorf E, Hegele RA, Descamps OS, Hopkins P, Nederveen AJ, Stroes ESG. Zheng KH, et al. Among authors: dasseux jl. Atherosclerosis. 2020 Oct;311:13-19. doi: 10.1016/j.atherosclerosis.2020.08.004. Epub 2020 Aug 29. Atherosclerosis. 2020. PMID: 32919280 Free article. Clinical Trial.
CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice.
Tardy C, Goffinet M, Boubekeur N, Ackermann R, Sy G, Bluteau A, Cholez G, Keyserling C, Lalwani N, Paolini JF, Dasseux JL, Barbaras R, Baron R. Tardy C, et al. Among authors: dasseux jl. Atherosclerosis. 2014 Jan;232(1):110-8. doi: 10.1016/j.atherosclerosis.2013.10.018. Epub 2013 Nov 8. Atherosclerosis. 2014. PMID: 24401224
The effect of an apolipoprotein A-I-containing high-density lipoprotein-mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholesterolemia: The Modifying Orphan Disease Evaluation (MODE) study.
Hovingh GK, Smits LP, Stefanutti C, Soran H, Kwok S, de Graaf J, Gaudet D, Keyserling CH, Klepp H, Frick J, Paolini JF, Dasseux JL, Kastelein JJ, Stroes ES. Hovingh GK, et al. Among authors: dasseux jl. Am Heart J. 2015 May;169(5):736-742.e1. doi: 10.1016/j.ahj.2015.01.008. Epub 2015 Jan 28. Am Heart J. 2015. PMID: 25965722 Clinical Trial.
HDL mimetic peptide CER-522 treatment regresses left ventricular diastolic dysfunction in cholesterol-fed rabbits.
Merlet N, Busseuil D, Mihalache-Avram T, Mecteau M, Shi Y, Nachar W, Brand G, Brodeur MR, Charpentier D, Rhainds D, Sy G, Schwendeman A, Lalwani N, Dasseux JL, Rhéaume E, Tardif JC. Merlet N, et al. Among authors: dasseux jl. Int J Cardiol. 2016 Jul 15;215:364-71. doi: 10.1016/j.ijcard.2016.04.029. Epub 2016 Apr 12. Int J Cardiol. 2016. PMID: 27128563
29 results