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Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.
Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, Lowary TL, Mahal LK, Riddell MR, Macauley MS. Schmidt EN, et al. Among authors: daskhan gc. Nat Commun. 2023 Apr 22;14(1):2327. doi: 10.1038/s41467-023-38030-6. Nat Commun. 2023. PMID: 37087495 Free PMC article.
Targeting CD22 on memory B cells to induce tolerance to peanut allergens.
Hardy LC, Smeekens JM, Raghuwanshi D, Sarkar S, Daskhan GC, Rogers S, Nycholat C, Maleki S, Burks AW, Paulson JC, Macauley MS, Kulis MD. Hardy LC, et al. Among authors: daskhan gc. J Allergy Clin Immunol. 2022 Dec;150(6):1476-1485.e4. doi: 10.1016/j.jaci.2022.06.022. Epub 2022 Jul 14. J Allergy Clin Immunol. 2022. PMID: 35839842 Free PMC article.
Anti-inflammatory role of GM1 and other gangliosides on microglia.
Galleguillos D, Wang Q, Steinberg N, Zaidi A, Shrivastava G, Dhami K, Daskhan GC, Schmidt EN, Dworsky-Fried Z, Giuliani F, Churchward M, Power C, Todd K, Taylor A, Macauley MS, Sipione S. Galleguillos D, et al. Among authors: daskhan gc. J Neuroinflammation. 2022 Jan 6;19(1):9. doi: 10.1186/s12974-021-02374-x. J Neuroinflammation. 2022. PMID: 34991625 Free PMC article.
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Nguyen L, McCord KA, Bui DT, Bouwman KM, Kitova EN, Elaish M, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yang TJ, Willows SD, Mason AL, Mahal LK, Lowary TL, West LJ, Hsu SD, Hobman T, Tompkins SM, Boons GJ, de Vries RP, Macauley MS, Klassen JS. Nguyen L, et al. Among authors: daskhan gc. Nat Chem Biol. 2022 Jan;18(1):81-90. doi: 10.1038/s41589-021-00924-1. Epub 2021 Nov 9. Nat Chem Biol. 2022. PMID: 34754101
Carbohydrate Sulfation As a Mechanism for Fine-Tuning Siglec Ligands.
Jung J, Enterina JR, Bui DT, Mozaneh F, Lin PH, Nitin, Kuo CW, Rodrigues E, Bhattacherjee A, Raeisimakiani P, Daskhan GC, St Laurent CD, Khoo KH, Mahal LK, Zandberg WF, Huang X, Klassen JS, Macauley MS. Jung J, et al. Among authors: daskhan gc. ACS Chem Biol. 2021 Nov 19;16(11):2673-2689. doi: 10.1021/acschembio.1c00501. Epub 2021 Oct 18. ACS Chem Biol. 2021. PMID: 34661385
Aminooxylated Carbohydrates: Synthesis and Applications.
Pifferi C, Daskhan GC, Fiore M, Shiao TC, Roy R, Renaudet O. Pifferi C, et al. Among authors: daskhan gc. Chem Rev. 2017 Aug 9;117(15):9839-9873. doi: 10.1021/acs.chemrev.6b00733. Epub 2017 Jul 6. Chem Rev. 2017. PMID: 28682060 Review.
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