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Structural and molecular interactions of CCR5 inhibitors with CCR5.
Maeda K, Das D, Ogata-Aoki H, Nakata H, Miyakawa T, Tojo Y, Norman R, Takaoka Y, Ding J, Arnold GF, Arnold E, Mitsuya H. Maeda K, et al. Among authors: das d. J Biol Chem. 2006 May 5;281(18):12688-98. doi: 10.1074/jbc.M512688200. Epub 2006 Feb 13. J Biol Chem. 2006. PMID: 16476734 Free article.
CCR5 inhibitors: emergence, success, and challenges.
Maeda K, Das D, Nakata H, Mitsuya H. Maeda K, et al. Among authors: das d. Expert Opin Emerg Drugs. 2012 Jun;17(2):135-45. doi: 10.1517/14728214.2012.673584. Epub 2012 Apr 25. Expert Opin Emerg Drugs. 2012. PMID: 22533737 Review.
P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel nonpeptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Yedidi RS, Maeda K, Fyvie WS, Steffey M, Davis DA, Palmer I, Aoki M, Kaufman JD, Stahl SJ, Garimella H, Das D, Wingfield PT, Ghosh AK, Mitsuya H. Yedidi RS, et al. Among authors: das d. Antimicrob Agents Chemother. 2013 Oct;57(10):4920-7. doi: 10.1128/AAC.00868-13. Epub 2013 Jul 22. Antimicrob Agents Chemother. 2013. PMID: 23877703 Free PMC article.
A conserved hydrogen-bonding network of P2 bis-tetrahydrofuran-containing HIV-1 protease inhibitors (PIs) with a protease active-site amino acid backbone aids in their activity against PI-resistant HIV.
Yedidi RS, Garimella H, Aoki M, Aoki-Ogata H, Desai DV, Chang SB, Davis DA, Fyvie WS, Kaufman JD, Smith DW, Das D, Wingfield PT, Maeda K, Ghosh AK, Mitsuya H. Yedidi RS, et al. Among authors: das d. Antimicrob Agents Chemother. 2014 Jul;58(7):3679-88. doi: 10.1128/AAC.00107-14. Epub 2014 Apr 21. Antimicrob Agents Chemother. 2014. PMID: 24752271 Free PMC article.
3,853 results